Results 121 to 130 of about 23,023 (292)

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia   +17 more
wiley   +1 more source

Process optimization for the production of fish gelatin nanoparticles

open access: yes, 2017
Animal proteins have become an useful source for producing gelatin nanoparticles, due to its application in cosmetics and therapeutics. Gelatin nanoparticle (GNP) is an excellent biodegradable and biocompatible material.
Jaswir, Irwandi   +3 more
core  

Optimization of Gelatin Extraction and Physico-chemical Properties of Fish Skin and Bone Gelatin: Its Application to Panna Cotta Formulas

open access: yes, 2017
The utilization of fish processing waste for value-added by-products has attracted considerable attention. The present study aims to evaluate the gelatin extracted from fish skin and bone for application to Panna cotta products. The optimum conditions of
Sirikhwan Tinratat, Monnipha Sila-asna
core   +1 more source

On the Preparation of Gelatin from the Fish-skin (I)

open access: yesNIPPON SUISAN GAKKAISHI, 1949
We examined the effect of the temperature and time of extraction of the fish skin on the melting point and jelly strength of the gelatin obtained. The results of these experiments are shown in Tab. 1 and 2.
OYA, T., GEJO, N.
openaire   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

open access: yesAdvanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang   +17 more
wiley   +1 more source

Fish gelatin and its applications in selected pharmaceutical aspects as alternative source to pork gelatin

open access: yes, 2013
The demand for gelatin for food and pharmaceutical application is increasing because it is one of the most widely used food ingredients. Its applications in food manufacturing are very wide-ranging including enhancing the elasticity, firmness and ...
Abd Elgadir, Mohammed   +2 more
core  

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source

Protein-Intercalated Bentonite for Bio-composites

open access: yes, 2013
The application of clays in various fields such as agriculture, mining, construction, petroleum derivatives recovery, waste water treatment and material reinforcements is closely related to their unique properties including small particle size with high ...
Shamsuddin, Rashid
core  

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

open access: yesAdvanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza   +9 more
wiley   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

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