Results 151 to 160 of about 1,271,767 (280)

Siderophores Produced by the Fish Pathogen Flavobacterium columnare Strain MS-FC-4 Are Not Essential for Its Virulence. [PDF]

Appl Environ Microbiol, 2022
Conrad RA, Evenhuis JP, Lipscomb RS, Birkett C, McBride MJ.   +4 more
europepmc   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

In Vitro Screening of Butcher's Broom (<i>Ruscus aculeatus</i> L.) Cladodes and Aerial Parts Extracts Against Fish Pathogen Isolates. [PDF]

Vet Sci
Demirkale İ, Bikzad H, Etyemez Büyükdeveci M, Secer FS.   +3 more
europepmc   +1 more source

Rich resource environment of fish farms facilitates phenotypic variation and virulence in an opportunistic fish pathogen. [PDF]

Evol Appl, 2022
Pulkkinen K, Ketola T, Laakso J, Mappes J, Sundberg LR.   +4 more
europepmc   +1 more source

Fish Gut Sporeformers to Control Fish Pathogens

Frontiers in Marine Science, 2016
Santos Rafaela, Couto André, Oliva-Teles Aires, Saavedra Maria, Enes Paula, Serra Claudia   +5 more
openaire   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Characterization of a unique phosphopantetheinyl transferase (PPTase) in the fish pathogen Pseudomonas plecoglossicida. [PDF]

PLoS One
Chi Y, Jia T, Chen J, Mao Z.
europepmc   +1 more source

Two Type VI Secretion DNase Effectors are Utilized for Interbacterial Competition in the Fish Pathogen Pseudomonas plecoglossicida. [PDF]

Front Microbiol, 2022
Li Y, Yan X, Tao Z.
europepmc   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Genome architecture reveals hidden strain-level diversity in the highly conserved fish pathogen Nocardia seriolae. [PDF]

Access Microbiol
Islam SI, Shahed K, Ahamed MI, Mohammed H.   +3 more
europepmc   +1 more source