Results 181 to 190 of about 55,711 (306)

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang   +12 more
wiley   +1 more source

Chemotactic motility is required for invasion of the host by the fish pathogen Vibrio anguillarum

open access: yes, 1996
The role of the flagellum and motility in the virulence of the marine fish pathogen Vibrio anguillarum was examined. Non-motile mutants were generated by transposon mutagenesis. Infectivity studies revealed that disruption of the flagellum and subsequent
Wolf-Watz, H   +2 more
core  

Fish Gut Sporeformers to Control Fish Pathogens

open access: yesFrontiers in Marine Science, 2016
Santos Rafaela   +5 more
openaire   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

Infectious disease studies in zebrafish : the fish pathogen Edwardsiella tarda as a model system

open access: yes, 2011
In a world where bacterial infections are becoming harder and harder to fight due to rising antibiotic resistance, disease models that allow high throughput screening are needed more than ever. An ideal model organism for high throughput screening is the
Soest, J.J. van
core   +1 more source

Genetic and biochemical insights into siderophore biosynthesis in the marine fish pathogen Tenacibaculum maritimum. [PDF]

open access: yesSci Rep
Escribano MP   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy