Results 101 to 110 of about 953,033 (308)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Changing fish trade and demand patterns in developing countries and their significance for policy research [PDF]

Trends for major fisheries products are evaluated for the past two decades, using aggregate annual data. Major changes have been propelled by income growth, changes in preferences and health concerns about meat in developed countries, leading to ...
Courbois, Claude, Delgado, Christopher L.   +1 more
core  

Investment prospects of fish farming in the Jos-Plateau, Nigeria [PDF]

, 1987
The investment prospects of fish farming in the Jos-Plateau, Nigeria, strategically located in about the centre of the country are discussed with special reference to its numerous abandoned mine lakes and the tripartite role of government, universities ...
Ufodike, E.B.C., Wade, J.W.
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

The effect of low temperatures and osmotic stress on the growth of lactic acid bacteria

Siberian Journal of Life Sciences and Agriculture
Background. To date, the use of lactic acid bacteria has not found wide industrial application in the production of fish products. At the same time, the scientific direction associated with the development and use of bacterial cultures for the processing
Anna P. Nikiforova, Irina S. Khamagaeva
doaj   +1 more source

A Study on Consumer Behaviour at Organized Fish Retail Outlet [PDF]

Indian consumers have been buying fish from the unhygienic fish markets, but of late fish has become available at many of the multi-format retail outlets. Consumers’ behaviour at organized fish retail outlets in Mumbai has been studied.
Ananthan, P.S., Debnath, Biswajit, Mugaonkar, Pankajkumar Hanmantrao, Samal, Suman Sekhar   +3 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Impact of environmental contaminants in fish on cell death and oxidative stress using in vivo, in vitro, and molecular docking

Food & Nutrition Research
Background: Fish species from the Red Sea constitute excellent food sources but may be unsafe to consume because their bioaccumulation of iron (Fe) is greater than the recommended concentration.
Saber Abdelkader Saïdi, Othman Ahmed Alghamdi, Mohiuddin Khan Warsi, ElFeki Abdelfattah, Jos van Pelt   +4 more
doaj   +1 more source

Marketing of value-added products from silver carp and involvement of rural people in the production and marketing chain [PDF]

, 2005
Cost-profit analysis and market testing of some value-added products from silver carp such as fish mince block, fish sausage, fish ball, fish stick and fish burger were analyzed during April 2001 to March 2002.
Alam, A.K.M.N.
core