Results 81 to 90 of about 3,851,994 (282)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

A Study on Consumer Behaviour at Organized Fish Retail Outlet [PDF]

open access: yes
Indian consumers have been buying fish from the unhygienic fish markets, but of late fish has become available at many of the multi-format retail outlets. Consumers’ behaviour at organized fish retail outlets in Mumbai has been studied.
Mugaonkar, Pankajkumar Hanmantrao   +3 more
core  

Storage of vacuum-packaged smoked bologna sausage prepared from Nile tilapia

open access: yesActa Scientiarum: Technology, 2014
Changes in smoked bologna sausage manufactured with Niletilapia (Oreochromis niloticus), and wheat fibers in refrigerated storage (6 ± 2°C) during 30 days were evaluated.
Dayse Aline Ferreira Silva Bartolomeu   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

National fish, wildlife and plants climate adaptation strategy

open access: yes, 2013
The purpose of the National Fish, Wildlife and Plants Climate Adaptation Strategy is to inspire and enable natural resource administrators, elected officials, and other decision makers to take action to adapt to a changing climate.
National Fish, Wildlife and Plants Climate adaptation Partnership
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Celebrating the Wildlife and Sport Fish Restoration program: 75 years of conservation and partnership success

open access: yes, 2013
Seventy-five years of successful wildlife management is the remarkable legacy of the Pittman-Robertson Wildlife Restoration Act, and the cause of our 75th celebration. Along with the Dingell-Johnson Sport Fish Restoration Act, it is the foundation of the
U.S. Fish and Wildlife Service
core  

The EAEU Aquaculture Market: The State, Problems and Prospects of Development

open access: yesRUDN Journal of Economics
Currently, fish and fish products occupy an important place in the global food market. Recently, the global volumes of caught fish and artificially grown fish have almost equaled, and the latter is showing steady growth. This trend, in the context of the
Aleksey O. Yakimovich
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Changing fish trade and demand patterns in developing countries and their significance for policy research [PDF]

open access: yes
Trends for major fisheries products are evaluated for the past two decades, using aggregate annual data. Major changes have been propelled by income growth, changes in preferences and health concerns about meat in developed countries, leading to ...
Delgado, Christopher L.   +1 more
core  

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