Results 81 to 90 of about 433,957 (310)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Assessment of Germplasm Improvement in Three Farmed Grass Carp Populations Based on Genetic Variability

open access: yesBiology
The assessment of genetic improvement was comprehensively analyzed using the mtDNA Cyt b gene and SSR markers among three farmed grass carp populations caught in May 2024.
Zhongyuan Shen   +14 more
doaj   +1 more source

The fish stocks in Uganda aquatic systems: opportunities and challenges for transformation [PDF]

open access: yes, 2005
The status of fish stocks in a water body at any one time is a function of several factors affecting the production of fish in that water body. These include: total number (abundance) and biomass(weight) present, growth (size and age), recruitment (the ...
Balirwa, J.S., Kamanyi, J.R.
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Biological data from post mortem analysis of otters in Hungary [PDF]

open access: yes, 2008
In this paper we examined the characteristics of reproduction parameters, stomach content and inner organ weights on carcasses (male, n=67, female n=57, unknown n=3) of otters (Lutra lutra) collected in Hungary between 1999 and 2006.
Lanszki, József   +3 more
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Editorial: Methodological approaches for fish reproduction management. [PDF]

open access: yesFront Physiol, 2023
Mechaly AS   +3 more
europepmc   +1 more source

The Ultraviolet Filter 3-Benzylidene Camphor Adversely Affects Reproduction in Fathead Minnow (Pimephales promelas) [PDF]

open access: yes, 2017
The ultraviolet (UV) filter 3-benzylidene camphor (3BC) is used in personal care products and in a number of materials for UV protection. 3BC has been shown in vitro and in vivo in fish to be estrogenic, but possible effects on fertility and reproduction
Fent, Karl   +2 more
core  

Reproductive Endocrinology of Fishes [PDF]

open access: yesAmerican Zoologist, 1973
While evidence is currently lacking for the agnatha and elasmobranchs, the release of pituitary gonadotropin by the teleost pituitary appears to be under stimulatory control by the hypothalamus. Gonadotropin has to date only been purified from teleost pituitary glands.
openaire   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy