Results 101 to 110 of about 16,637,647 (281)
In lieu of an abstract, below is the essay\u27s first paragraph. I began my journey at St. John Fisher College in the fall of 2003; the education I received from Fisher was invaluable.
Hall, Shawn
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Information-Geometric Models in Data Analysis and Physics II
This paper continues the development of information-geometric models for data analysis and physics by focusing on their formulation and interpretation through variational principles.
D. Bernal-Casas, José M. Oller
doaj +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Structures in Sound: Analysis of Classical Music Using the Information Length
We show that music is represented by fluctuations away from the minimum path through statistical space. Our key idea is to envision music as the evolution of a non-equilibrium system and to construct probability distribution functions (PDFs) from musical
Schuyler Nicholson, Eun-jin Kim
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Fourth And Fifth Order Efficiency: Fisher Information
Loss of (Fisher) information, whose concept was defined by Fisher, is one of important measures of asymptotic efficiency. Based on Fisher information, this paper studies fourth and fifth order asymptotic efficiency of estimators in a curved exponential ...
Yutaka Kano, Fisher Information
core
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Copy of John Fisher's diary, made by him, 1776-1777
Typescript copy of diary entries made by John Fisher (1755-1843), the great-grandfather of George Brayton Fisher, for a period covering 14 July 1776 to 10 August 1777.
Fisher, John, 1755-1843;
core
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Fisher Information and Spline Interpolation
It is shown that among all cumulative distribution functions passing through $k \geqq 2$ given points there is a unique one with minimal Fisher information; it is obtained by a curious type of spline interpolation. This answers some questions raisd by D. G. Kendall and J. W. Tukey.
openaire +2 more sources

