Results 71 to 80 of about 739,441 (301)

Asymptotic fisher information in order statistics of geometric distribution [PDF]

open access: yesIranian Journal of Numerical Analysis and Optimization, 2009
In this paper, the geometric distribution is considered. The means, variances, and covariances of its order statistics are derived. The Fisher information in any set of order statistics in any distribution can be represented as a sum of Fisher ...
M. Roozbeh, S. M. M. Tabatabaey
doaj   +1 more source

An Algorithm for Estimating the Signal Frequency at the Output of a Channel with a Controlled Information Flow under Phase Noise Conditions

open access: yesМоделирование и анализ информационных систем, 2021
Research in the field of efficient frequency estimation algorithms is of great interest. The reason for this is the redistribution of the role of additive and phase noise in many modern radio-engineering applications.
Leonid Nikolaevich Kazakov   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Invariant Fisher information

open access: yesDifferential Geometry and its Applications, 1994
Let \(t = t(p,\omega): M \times \Omega \to \mathbb{R}^ k\) be a family of \(\mathbb{R}^ k\)-valued random variables parametrized by an \(n\)-dimensional manifold \(M\), where \(x = (x^ 1,\dots,x^ n)\) is a chart around \(p \in M\), \(\Omega\) a probability space and \(\omega \in \Omega\).
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Connecting Fisher information to bulk entanglement in holography

open access: yesJournal of High Energy Physics, 2018
In the context of relating AdS/CFT to quantum information theory, we propose a holographic dual of Fisher information metric for mixed states in the boundary field theory.
Souvik Banerjee   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Extreme Fisher Information, Non-Equilibrium Thermodynamics and Reciprocity Relations

open access: yesEntropy, 2011
In employing MaxEnt, a crucial role is assigned to the reciprocity relations that relate the quantifier to be extremized (Shannon’s entropy S), the Lagrange multipliers that arise during the variational process, and the expectation values that constitute
Montserrat Casas   +3 more
doaj   +1 more source

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