Results 71 to 80 of about 16,637,647 (281)
Estimation of the Parameters of the New Weibull-Pareto Distribution Using Ranked Set Sampling
Statistica, 2020 The method of maximum likelihood estimation based on ranked set sampling (RSS) and some of its modifications is used to estimate the unknown parameters of the new Weibull-Pareto distribution.
Monjed H. Samuh +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Connecting Fisher information to bulk entanglement in holography
Journal of High Energy Physics, 2018 In the context of relating AdS/CFT to quantum information theory, we propose a holographic dual of Fisher information metric for mixed states in the boundary field theory.
Souvik Banerjee +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Extreme Fisher Information, Non-Equilibrium Thermodynamics and Reciprocity Relations
Entropy, 2011 In employing MaxEnt, a crucial role is assigned to the reciprocity relations that relate the quantifier to be extremized (Shannon’s entropy S), the Lagrange multipliers that arise during the variational process, and the expectation values that constitute
Montserrat Casas +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Letter to Snooky [Rosemary Fisher]
, 1945 A letter describing the requirements for Rosemary Snook's parents of Bournemouth, England, to approve their 18-year-old daughter's marriage to George Fisher, an American soldier during World War II.Brussels, Belgium Nov.
Fisher, George, 1923-2003
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
George Fisher at the Drawing Board Searching for Cartoon Ideas
, 1995 Cartoon by Fisher of a cartoonist holding his head in his hands and surrounded by cartoon images of well-known political figures. Woman's text bubble on recto: "No idea for a cartoon?
Fisher, George, 1923-2003
core +1 more source