Results 91 to 100 of about 892,982 (340)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Media advocacy for farm safety and health: current landscape and future directions

BMC Public Health
Background Within public health, media advocacy embraces the influence of new media and journalists in setting public agendas and promoting important public health programming and policies.
Pamela J. Milkovich, Sarah Perez-Sanz, Kim Garcia, Pamela Mejia, Andrew Johnson, Julie A. Sorensen   +5 more
doaj   +1 more source

Magnetic ligand fishing using immobilized DPP-IV for identification of antidiabetic ligands in lingonberry extract

, 2021
Rita de Cássia Lemos Lima, Ulrike Böcker, Gordon J. McDougall, J. William Allwood, Nils Kristian Afseth, Sileshi Gizachew Wubshet   +5 more
openalex   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

DETERMINATION OF PROTEIN FRACTIONS IN THE BLOOD OF THE HIGH ECONOMIC VALUE FISH FARMED SPECIES IN ROMANIA

Scientific Papers Animal Science and Biotechnologies, 2023
In aquaculture, as in any other sector where work is carried out on live bodies, to get a high production yield depends upon maintenance and monitoring of an unaltered health condition of the biological material.
T. PATRICHE, N. PATRICHE
doaj  

The impact of fishing‐induced mortality on the evolution of alternative life‐history tactics in brook charr [PDF]

, 2008
Veronique Thériault, Erin S. Dunlop, Ulf Dieckmann, Louis Bernatchez, Julian J. Dodson   +4 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Big fish, little fish [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2016
Dirk J, Varelmann, Michael N, D'Ambra
openaire   +2 more sources

Key variables for sustainable management of The Belida (Chitala lopis) Fishery at inland waters in Kapuas Hulu Regency [PDF]

BIO Web of Conferences
Sustainable management of the Belida (Chitala lopis) fishery at inland waters in Kapuas Hulu Regency is a process of improving environmental approvals.
Hamid Abdul, Purbayanto Ari, Kusmana Cecep, Wisudo Sugeng Hari   +3 more
doaj   +1 more source