Results 81 to 90 of about 863,290 (309)

Examining the Tragedy of the Commons Dilemma: Looking at the New Hampshire Fishing Industry [PDF]

open access: yes, 2019
The Tragedy of the Commons is a widely known problem debated amongst economists for years. Even the topic of the Tragedy of the Commons when applied to fishing has been debated several times.
Brown, Peter A
core   +1 more source

Hog Daddy and the Walls of Steel: Catch Shares and Ecosystem Change in the New England Groundfishery [PDF]

open access: yes, 2014
The U.S. National Oceanic and Atmospheric Administration implemented marketbased fishery management in the New England groundfishery as catch shares, controlling aggregate harvests through tradable annual catch quotas allocated to fishing groups called ...
Brewer, Jennifer F
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Classification of Areas Suitable for Fish Farming Using Geotechnology and Multi-Criteria Analysis

open access: yesISPRS International Journal of Geo-Information, 2019
This study proposed a method for identifying areas appropriate for fish farming in ground-excavated ponds using data obtained from public institutions.
Humberto Rodrigues Francisco   +2 more
doaj   +1 more source

Livelihood Diversification In Coastal and Inland Fishing Communities: Misconceptions, Evidence and Implications for Fisheries Management [PDF]

open access: yes, 2008
This is the working paper regarding the Sustainable Fisheries Livelihoods Programme (SFLP). Diversification is a process by which households engage in multiple income generating activities.
Cécile Brugère   +2 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Estimates of numbers of White sharks (Carcharodon carcharias) in Eastern and Southern South Africa : a post-moratorium assessment [PDF]

open access: yes, 2004
A moratorium was placed on fishing for white sharks (Carcharodon carcharias) in South Africa in 1991 prior to knowing the population status of this species.
Tress, Mary Elizabeth
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy