Results 111 to 120 of about 231,819 (317)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Report on the Spiny lobster fishery: Summary of Fishing Activity for the 2015-2016 season.

open access: yes, 2016
The Seychelles artisanal spiny lobster fishery targets shallow water lobster stocks around the main granitic islands. The main species of lobsters caught are Homard Grosse Tete ( Panulirus penicillatus ), Homard Rouge ( P ...

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Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Fishing Power Functions in Aggregate Bioeconomic Models

open access: yes
A method for estimating fishing power in the Beverton-Holt tradition in the absence of firm-level data is developed. This enables the construction of a standardized measure of fishing effort that can facilitate the analysis and implementation of various ...
Taylor, Timothy G., Prochaska, Fred J.
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Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Economic valuation of recreational fishing in Western Australia

open access: yes
Allocation of fish resource is a controversial subject. Decision making is partly made difficult by the lack of knowledge on recreational fishing preferences and the value of fishing opportunities.
Raguragavan, Jananee   +2 more
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Seychelles Fishing Authority Annual report 2014.

open access: yes, 2017
2014 marked the 30th anniversary of the formation of the Seychelles Fishing Authority (SFA) with the enactment of the Seychelles Fishing Authority (Establishment) Act 1984.

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Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Seychelles Fishing Authority tuna bulletin year 2003

open access: yes, 2005
Data used to generate the tables and figures presented here are based on daily catch and effort forms (logbooks) returned from fishing vessels that are licensed to fish in the Seychelles EEZ and from data collected via the tuna sampling programme ...

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