Results 101 to 110 of about 856,392 (338)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Environmental Conditions Assessment for the Carp Cultured in Floating Cages on the Irrigation Canals

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Aquaculture in cages is considered an alternative to fishing in natural waters, by increasing fish production and using new water resources. This production method confers efficiency for fish farming and varies according to the ecological quality of the ...
Veta Nistor   +5 more
doaj  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Fisheries statistical bulletin, Kainji Lake, Nigeria, 1998 [PDF]

open access: yes, 1999
A tabulated summary is presented of the main fisheries data collected to date (1998) by the Nigerian-German Kainji Lake Fisheries Promotion Project, together with a current overview of the fishery.

core  

Key variables for sustainable management of The Belida (Chitala lopis) Fishery at inland waters in Kapuas Hulu Regency [PDF]

open access: yesBIO Web of Conferences
Sustainable management of the Belida (Chitala lopis) fishery at inland waters in Kapuas Hulu Regency is a process of improving environmental approvals.
Hamid Abdul   +3 more
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

FAQ: Illegal, Unreported, and Unregulated Fishing [PDF]

open access: yes, 2013
Pressure on the world's fish stocks is at an all-time high, and although most industrial fishing operations are within the law, some take to the seas fully intending to steal fish. But how is illegal fishing defined?

core  

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