Results 71 to 80 of about 107,170 (342)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Seasonal Changes in Blood Parameters in Juvenile Cyprinus carpio

Scientific Papers Animal Science and Biotechnologies, 2023
Temporal variations in the biochemical and haematological parameters of blood must be taken into account as it is a useful indicator for assessing the nutritional status, non-specific immunity and health of fish in general.
Elena Eugenia Mocanu, Floricel Maricel Dima, Viorica Savin, Marcel Daniel Popa   +3 more
doaj  

Key variables for sustainable management of The Belida (Chitala lopis) Fishery at inland waters in Kapuas Hulu Regency [PDF]

BIO Web of Conferences
Sustainable management of the Belida (Chitala lopis) fishery at inland waters in Kapuas Hulu Regency is a process of improving environmental approvals.
Hamid Abdul, Purbayanto Ari, Kusmana Cecep, Wisudo Sugeng Hari   +3 more
doaj   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

New univariate characterization of fish community size structure improves precision beyond the Large Fish Indicator [PDF]

arXiv, 2017
The size structure of fish-communities is an emergent high-level property of marine food webs responsive to changes in structure and function. To measure this food web property using data arising from routine fisheries surveys, a simple metric known as Typical Length has been proposed as more suitable than the Large Fish Indicator, which has been ...
arxiv  

Counting Fish and Dolphins in Sonar Images Using Deep Learning [PDF]

arXiv, 2020
Deep learning provides the opportunity to improve upon conflicting reports considering the relationship between the Amazon river's fish and dolphin abundance and reduced canopy cover as a result of deforestation. Current methods of fish and dolphin abundance estimates are performed by on-site sampling using visual and capture/release strategies.
arxiv  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Influence of Phytogenic Additives on Growth Parameters and Meat Biochemistry in Cyprinus carpio

Scientific Papers Animal Science and Biotechnologies, 2023
Over time, antibiotics have been used in aquaculture to control fish diseases. Improper and sometimes unjustified use of them has raised concerns about their effectiveness and the possibility of resistant bacterial strains development.
Viorica Savin, Elena Mocanu, Floricel Dima, Neculai Patriche, Marcel Daniel Popa, Victor Cristea   +5 more
doaj  

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source