Results 71 to 80 of about 107,170 (342)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Seasonal Changes in Blood Parameters in Juvenile Cyprinus carpio

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Temporal variations in the biochemical and haematological parameters of blood must be taken into account as it is a useful indicator for assessing the nutritional status, non-specific immunity and health of fish in general.
Elena Eugenia Mocanu   +3 more
doaj  

Key variables for sustainable management of The Belida (Chitala lopis) Fishery at inland waters in Kapuas Hulu Regency [PDF]

open access: yesBIO Web of Conferences
Sustainable management of the Belida (Chitala lopis) fishery at inland waters in Kapuas Hulu Regency is a process of improving environmental approvals.
Hamid Abdul   +3 more
doaj   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

New univariate characterization of fish community size structure improves precision beyond the Large Fish Indicator [PDF]

open access: yesarXiv, 2017
The size structure of fish-communities is an emergent high-level property of marine food webs responsive to changes in structure and function. To measure this food web property using data arising from routine fisheries surveys, a simple metric known as Typical Length has been proposed as more suitable than the Large Fish Indicator, which has been ...
arxiv  

Counting Fish and Dolphins in Sonar Images Using Deep Learning [PDF]

open access: yesarXiv, 2020
Deep learning provides the opportunity to improve upon conflicting reports considering the relationship between the Amazon river's fish and dolphin abundance and reduced canopy cover as a result of deforestation. Current methods of fish and dolphin abundance estimates are performed by on-site sampling using visual and capture/release strategies.
arxiv  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Influence of Phytogenic Additives on Growth Parameters and Meat Biochemistry in Cyprinus carpio

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Over time, antibiotics have been used in aquaculture to control fish diseases. Improper and sometimes unjustified use of them has raised concerns about their effectiveness and the possibility of resistant bacterial strains development.
Viorica Savin   +5 more
doaj  

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

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