Results 161 to 170 of about 92,954 (262)

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

Mitophagy-mediated immune evasion: Shared strategies of pathogens. [PDF]

Redox Biol
Li J, Li W, Wang D, Liu Y.
europepmc   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Traditional Chinese medicine-derived monomers protect chondrocytes and delay osteoarthritis progression by regulating mitochondrial quality control. [PDF]

Front Mol Biosci
Yang X, Li Y.
europepmc   +1 more source

Inequalities in intraspecific plant–lemur interactions drive seed dispersal patterns

Oikos, EarlyView.
Biotic interactions occur between individuals and accumulate to shape species‐level interaction structure across a community. Skewed interaction structures, where a few individuals are highly connected and most have few interactions, are increasingly identified at the individual‐level.
Jadelys Tonos, Hasinavalona Rakotoarisoa, Onja H. Razafindratsima   +2 more
wiley   +1 more source

m6A-Mediated epitranscriptional reprogramming drives cardiac fibrosis by suppressing PGC-1α and boosting mitochondrial fission. [PDF]

J Transl Med
Cao XY, Tu B, Cao ZR, Liu F, Yan G, Dong J, Huang QW, Li ZJ, Liu QY, Leng JJ, Yu WC, Bie MJ, Wang XW, Jiang YJ.   +13 more
europepmc   +1 more source

Age ratio in groups of a social ungulate affects epizoochorous dispersal and diaspore exchanges

Oikos, EarlyView.
Animal‐mediated seed dispersal is a key process in plant population dynamics, species distribution and ecosystem functioning. As long‐distance dispersal agents, ungulates help to maintain native plant populations facing abiotic changes in their habitat and habitat fragmentation or habitat loss.
Antoine Roux, Cloé Balson, Morgane Audiguier, Marie Battista, Didier Marcon, Olivier Pays, Christophe Baltzinger   +6 more
wiley   +1 more source

MTFR2 regulated the proliferation, apoptosis, migration, and invasion of endometrial cancer cells through the Drp1/MFN1 signaling pathway mediated mitochondrial fission. [PDF]

Transl Cancer Res
Bai X, Wei M, Wang Q, Yang Y.
europepmc   +1 more source

Passive Acoustic Identification of Social Groups in the Hainan Gibbon

Remote Sensing in Ecology and Conservation, EarlyView.
Passive acoustic monitoring offers a non‐invasive means of assessing visually hard‐to‐survey wildlife species with distinctive vocalizations. We evaluated whether deep learning can identify Hainan gibbon (Nomascus hainanus) social groups from their calls.
Emmanuel Kabuga, Emmanuel Dufourq, Nonhlanhla L. Luphade, Samuel T. Turvey, Heidi Ma, Susan M. Cheyne, Hui Liu, Jessica V. Bryant, Qing Chen, Wenyong Li, Zhiwei Liu, Zhaoli Zhou, Stefan Britz, Bubacarr Bah, Ian Durbach   +14 more
wiley   +1 more source

Mitochondrial homeostasis imbalance-triggered PANoptosis in traumatic brain and spinal cord injury: from mechanism to therapeutic strategies. [PDF]

Redox Biol
Ye Y, Feng Z, Huang P, Su X, Lu C, Yu Y, Li L, Wang J, Li X.   +8 more
europepmc   +1 more source