Results 61 to 70 of about 799,230 (312)

Spatiotemporal and Ground Reaction Force Determinants of Sprint Acceleration in Adolescent Male Baseball Players [PDF]

The Asian Journal of Kinesiology
OBJECTIVES This study examined the relationships of changes in running speed with spatiotemporal (e.g., step length and frequency) and ground reaction force (GRF) variables during a 30-m sprint acceleration in adolescent baseball players to identify the ...
Tomoya Hirano, Chiharu Suzuki, Keisuke Oosawa, Hiroo Takahashi, Ryu Nagahara   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Alcohol and tobacco dependence among medical practitioners

European Psychiatry
Introduction Excessive use of tobacco, alcohol and other illicit drugs has a negative impact on the physical and mental health and work capacity of users. Physicians are no exception to these dreadful practices.
A. Belkahla, D. Brahim, I. Yaich, C. Ben Said, A. Ghenim, M. Mersni, H. Ben Said, N. Mechergui, I. Youssef, G. Bahri, N. Bram, N. Ladhari   +11 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Spatiotemporal and Kinetic Determinants of Sprint Acceleration Performance in Soccer Players

Sports, 2018
We aimed to elucidate spatiotemporal and kinetic determinants of sprint acceleration performance in soccer players. Thirty-seven male soccer players performed 60-m sprints.
Munenori Murata, Yohei Takai, Hiroaki Kanehisa, Tetsuo Fukunaga, Ryu Nagahara   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Does living in urban or rural settings affect aspects of physical fitness in children? An allometric approach. [PDF]

, 2005
The aim of this study was to investigate physical fitness in relation to fatness in urban and rural Greek children by means of allometric scaling. METHODS: The sample consisted of 360 (189 urban and 171 rural; age 12.3+/-0.42 years) boys and 247 (125 ...
Tsimeas, P. D., Koutedakis, Yiannis, Tsiokanos, A.L., Tsimeas, P.D., Kellis, S., Tsimeas, Panagiotis D., Koutedakis, Y., Tsiokanos, Athanasios, Kellis, Spiros, Tsigilis, N., Tsiokanos, A. L.   +10 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Biomechanical determinants of ground contact time and jump height during drop jumps in male athletes [PDF]

PeerJ
Background Drop jump (DJ) performance is underpinned by a complex interplay of biomechanical factors occurring during the eccentric and concentric phases.
Hirotomo Kubota, Kohdai Kishi, Taiyo Kurita, Yohei Takai   +3 more
doaj   +2 more sources

ABSOLUTE FITNESS, RELATIVE FITNESS, AND UTILITY [PDF]

Evolution, 2007
It is well known that (1) natural selection typically favors an allele with both a large mean fitness and a small variance in fitness; and (2) investors typically prefer a portfolio with both a large mean return and a small variance in returns. In the case of investors, this mean-variance trade-off reflects risk aversion; in the case of evolution, the ...
openaire   +2 more sources