Results 61 to 70 of about 1,555,668 (297)

大学トレーニングセンターにおけるトレーニング器具の衛生状況について [PDF]

open access: yes, 2018
University training center users include those attempting to improve their health. There are reports of a tendency of annual increase in the number of elderly people visiting fitness clubs.
田中 淳, 畑島 紀昭
core   +1 more source

Spatiotemporal and Ground Reaction Force Determinants of Sprint Acceleration in Adolescent Male Baseball Players [PDF]

open access: yesThe Asian Journal of Kinesiology
OBJECTIVES This study examined the relationships of changes in running speed with spatiotemporal (e.g., step length and frequency) and ground reaction force (GRF) variables during a 30-m sprint acceleration in adolescent baseball players to identify the ...
Tomoya Hirano   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Theoretical investigation into the origins of multicellularity : a thesis presented in partial fulfilment of the requirements for the degree of PhD in Theoretical Biology at Massey University, Albany, New Zealand [PDF]

open access: yes, 2015
Evolution of multicellularity is a major event in the history of life. The first step is the emergence of collectives of cooperating cells. Cooperation is generally costly to cooperators, thus, non-cooperators have a selective advantage. I investigated
Pichugin, Yuriy
core  

Analysis of adaptive walks on NK fitness landscapes with different interaction schemes

open access: yes, 2015
Fitness landscapes are genotype to fitness mappings commonly used in evolutionary biology and computer science which are closely related to spin glass models.
Krug, Joachim, Nowak, Stefan
core   +1 more source

Darwinian fitness

open access: yesTheoretical Population Biology, 2007
The term Darwinian fitness refers to the capacity of a variant type to invade and displace the resident population in competition for available resources. Classical models of this dynamical process claim that competitive outcome is a deterministic event which is regulated by the population growth rate, called the Malthusian parameter.
Demetrius, Lloyd, Ziehe, Martin
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Evolutionary dynamics of tumor progression with random fitness values

open access: yes, 2010
Most human tumors result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis. Other mutations,
Becskei   +43 more
core   +1 more source

‘Virtual’ mentoring: can the principle of cognitive pairing increase its effectiveness? [PDF]

open access: yesInternational Journal of Evidence Based Coaching and Mentoring, 2006
This paper is based on the experiences of completing a virtual mentoring programme within the higher education sector that used the principle of ‘cognitive pairing’ to enable the rapid establishment of high quality mentoring relationships.
Fiona Beddoes-Jones, Julia Miller
doaj  

Differences in circulating fatty acid-binding protein 4 concentration in the venous and capillary blood immediately after acute exercise

open access: yesJournal of Physiological Anthropology, 2021
Background Circulating fatty acid-binding protein 4 (FABP4) is a marker for various diseases. It would be highly useful to have simple and less invasive techniques for the assessment of FABP4 concentrations in the clinical research setting.
Shigeharu Numao   +3 more
doaj   +1 more source

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