Results 81 to 90 of about 684,983 (316)

Peritoneal mesothelioma associated with bladder cancer and occupational exposure to asbestos: A case report

Clinical Case Reports, 2020
Mesothelioma is a rare tumor usually located on the pleura. In this typical location, it is closely linked to asbestos exposure. However, in other locations such as in peritoneal mesothelioma, the association to asbestos remains unusual.
Dorra Brahim, Najla Mechergui, Hanene Ben Said, Dhouha Cherif, Nizar Ladhari, Imen Youssef   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Effect of deworming on physical fitness of school-aged children in Yunnan, China : a double-blind, randomized, placebo-controlled trial [PDF]

, 2014
There is considerable debate on the health impacts of soil-transmitted helminth infections. We assessed effects of deworming on physical fitness and strength of children in an area in Yunnan, People's Republic of China, where soil-transmitted ...
Peter Steinmann, Xiao-Nong Zhou (92570), Krauth, Stefanie J., Utzinger, Jürg, Peter Steinmann (92572), Fang-Wei Wu (596281), Krauth, Stefanie J, Jan Hattendorf (113923), Kriemler, Susi, Jin-Yong Jiang, Yap, Peiling, Fang-Wei Wu, Zun-Wei Du, Ran Chen (182828), Ran Chen, Xiao-Nong Zhou, Jürg Utzinger, Susi Kriemler (18250), Jin-Yong Jiang (204086), Zhou, Xiao-Nong, Stefanie J Krauth, Zun-Wei Du (204085), Wu, Fang-Wei, Du, Zun-Wei, Jürg Utzinger (39609), Steinmann, Peter, Jiang, Jin-Yong, Peiling Yap, Stefanie J. Krauth (108843), Chen, Ran, Susi Kriemler, Hattendorf, Jan, Peiling Yap (596280), Jan Hattendorf   +33 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Fitting without fittings

We show that all symplectically aspherical fillings of the unit cotangent bundle of a given odd-dimensional sphere are diffeomorphic to the corresponding unit co-disc bundle. The concept of fittings previously introduced is not needed.
Bimmermann, Johanna, Stratmann, Bernd, Zehmisch, Kai   +2 more
openaire   +2 more sources

Sports Medicine & Fitness News (1986 Summer)

, 1986
Sports Medicine Fitness Center. (1986). Sports Medicine & Fitness News (1986 Summer).
Sports Medicine Fitness Center
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Effects of aging on unloading-induced skeletal muscle atrophy and subsequent recovery in rats

Journal of Physical Fitness and Sports Medicine, 2013
Aged individuals with physiological muscle atrophy (sarcopenia) are likely forced into an unloading condition of inactivity such as bed rest and limb-immobilization.
Hideki Yamauchi, Yuki Takeda, Shino Tsuruoka, Shigeru Takemori   +3 more
doaj   +1 more source

Sports Medicine & Fitness News (1983-01 and 02)

, 1983
Sports Medicine Fitness Center. (1983). Sports Medicine & Fitness News (1983-01 and 02).
Sports Medicine Fitness Center
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source