Results 101 to 110 of about 684,983 (316)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Difficulties in assessing the medical fitness of workers with mood disorders : A study of 101 cases

European Psychiatry
Introduction Assessing the medical fitness of workers with mood disorders remains a topical issue, because of its organizational, socioeconomic and professional impact.
S. Chemingui, D. Brahim, M. Mersni, N. Mechergui, M. Methni, H. Ben Said, I. Youssef, G. Bahri, I. Yaich, C. Ben Said, N. Bram, N. Ladhari   +11 more
doaj   +1 more source

USSF News: USSF forms partnership with Springfield College (Summer 1996)

, 1996
This is the Summer 1996 USSF. It is four pages long. On Page one and two is a story about the partnership of Springfield College and the United States Sports and Fitness Center for the Disabled.
United States Sports and Fitness Center for the Disabled;
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Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Identification of key performance parameters and development of a youth badminton performance index in male youth players

Scientific Reports
Youth badminton performance involves an interplay of structural, physiological, training, and experiential factors more than a stand-alone measure like competition ranking.
Mohammad Firdaus Mohd Israj, Nur Syazwani Ibrahim, Nor Ikhmar Madarsa, Siti Nor Alia Kartika Mohamed Shaihan, Rozita Abdul Latif, Mohd Syaiful Nizam Abu Hassan, Ahmad Bisyri Husin Musawi Maliki   +6 more
doaj   +1 more source

Self-Reported Physical Activity Among Individuals with Diabetes Mellitus in Germany—Identifying Potential Barriers and Facilitators

Diabetology
Background/Objectives: Physical activity is a cornerstone of diabetes mellitus (DM) management and is strongly recommended in the American Diabetes Association (ADA)’s guidelines.
Frederike Maria Meuffels, Celine Lichtmess, Thorsten Kreutz, Steffen Held, Christian Brinkmann   +4 more
doaj   +1 more source

Changes in Fitness, physical activity, fatness, and screen time: A longitudinal study in children and adolescents

, 2009
*_Objective:_* To analyze whether changes in Physical Activity Index (PAI), sedentary time (ST; TV and PC use), and Body Mass Index (BMI) made a significant contribution to longitudinal changes in Physical Fitness (PF) of children and adolescents ...
Clarice Martins, Lars Bo Andersen, Denisa Mendonça, Maria Paula Santos, Jose Ribeiro, Gustavo Silva, Jorge Mota, Luisa Aires   +7 more
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National physical education curriculum: motor and cardiovascular health related fitness in Greek adolescents. [PDF]

, 2007
Background: State school physical education (PE) programmes are common throughout Greece. However, it is not known if the main objectives of the Greek PE curriculum are achieved.
Bouziotas, Constantin, Koutedakis, Yiannis   +1 more
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USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Safety alert for treadmills in health & fitness facilities in Australia : Results from a pilot study of an observational audit tool

, 2016
Sekendiz, B ORCiD: 0000-0002-5657-0008Introduction: Design of a health/fitness facility is a crucial element in managing risks to its operators, users and others.
Eickhoff-Shemek, JM, Keyzer, Patrick, JM Eickhoff-Shemek (9879710), Dietrich, Joachim, CF Finch (9878888), Gray, Shannon E, SE Gray (9879707), Sekendiz, Betul, Gray, SE, Betul Sekendiz (9833729), Norton, K, J Dietrich (9866759), Norton, Kevin, Sekendiz, B, Eickhoff-Shemek, JoAnn M, Finch, CF, K Norton (9850571), P Keyzer (9866756), Dietrich, J, Keyzer, P, Finch, Caroline   +20 more
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