Results 111 to 120 of about 799,230 (312)

Sports Medicine & Fitness News (1983-07 and 08)

, 1983
Sports Medicine Fitness Center. (1983). Sports Medicine & Fitness News (1983-07 and 08).
Sports Medicine Fitness Center
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PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Fitness Application

This thesis explores the development of a fitness application designed to enhance trainer-trainee interactions. It incorporates key features such as workout and meal plan assignments, progress tracking, and feedback management.
Taiwo, Tolulope Sheriff
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Sports Medicine & Fitness News (1984-03 and 04)

, 1983
Sports Medicine Fitness Center. (1983). Sports Medicine & Fitness News (1984-03 and 04).
Sports Medicine Fitness Center
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Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

"Fits" [PDF]

BMJ, 1955
openaire   +2 more sources

Safety alert for treadmills in health & fitness facilities in Australia : Results from a pilot study of an observational audit tool

, 2016
Sekendiz, B ORCiD: 0000-0002-5657-0008Introduction: Design of a health/fitness facility is a crucial element in managing risks to its operators, users and others.
Eickhoff-Shemek, JM, Keyzer, Patrick, JM Eickhoff-Shemek (9879710), Dietrich, Joachim, CF Finch (9878888), Gray, Shannon E, SE Gray (9879707), Sekendiz, Betul, Gray, SE, Betul Sekendiz (9833729), Norton, K, J Dietrich (9866759), Norton, Kevin, Sekendiz, B, Eickhoff-Shemek, JoAnn M, Finch, CF, K Norton (9850571), P Keyzer (9866756), Dietrich, J, Keyzer, P, Finch, Caroline   +20 more
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COMPONENTS OF PHYSICAL FITNESS DIET AND NUTRITION

, 2021
Absolute power Fitness is an allencompassing wellbeing way to deal with upgrading warrior wellbeing and versatility. Nutritional Fitness is a fundamental segment of complete power Fitness as poor nourishment degrades mission readiness and adds to an ...
COMPONENTS OF PHYSICAL FITNESS DIET AND NUTRITION
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In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source