Results 131 to 140 of about 114,985 (325)
Duties and Rights to the Marti how training and performance of Cuban teachers
Revista MENDIVE, 2003 It is intended to expand the horizon of use and management of Marti's ideas by teachers so that, in correspondence with the realization of political and ideological work required in our classes, use the wise way of saying things of our greatest teacher ,
Juan José León Coro
doaj
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Fitting classes and products of totally permutable groups
, 2002 The second and third authors have been supported by Proyecto PB 97-0674-C02-02 of DGESIC, Ministerio de Educación y Cultura, Spain.Hauck, P.; Martínez Pastor, A.; Pérez-Ramos, M. (2002). Fitting classes and products of totally permutable groups.
Hauck, P. +6 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Application of the class-balancing strategies with bootstrapping for fitting logistic regression models for post-fire tree mortality in South Korea [PDF]
, 2023 Kyungrok Hwang +2 more
openalex +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
On the Problem of Frattini Duality in the Theory of Fitting Classes [PDF]
, 2019 We study the application of the Frattini duality to the description of multiple local Fitting classes. In particular, we establish a necessary and sufficient condition for the local Fitting class to be a ...
Zhao, Sh., Vorob’ev, N.T., Yang, N.
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source