Results 111 to 120 of about 114,985 (325)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A note on Hall closure of metanilpotent fitting classes [PDF]
, 1996 Martin Menth
openalex +1 more source
Parallelization and vectorization of ROOT fitting classes
, 2018 We introduce parallelization and vectorization in ROOT mathematical and statistical libraries in order to take full advantage of new computer architectures and to maximize the CPU usage with an increasing amount of data to analyze. As part of this effort,
Valls Pla, X, Moneta, L
core +1 more source
On Stone sublattices of the lattice of totally local Fitting classes
, 2007 Totally local Fitting classes with a Stone lattice of totally local Fitting subclasses are ...
Vorob’ev, N.N., Skiba, A.N.
core +2 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Correction to: Stickelberger ideals and Fitting ideals of class groups for abelian number fields [PDF]
, 2019 Masato Kurihara, Takashi Miura
openalex +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Study on Wind Profile Characteristics Using Cluster Analysis
AtmosphereThe accurate characterization of typhoon wind profile properties is of great importance in the field of wind engineering and wind design of high-rise structures.
Yanru Wang +7 more
doaj +1 more source