Results 41 to 50 of about 3,343 (255)

SYSTEM FOR ROTARY-AXIS DIAGNOSTICS IN FIVE-AXIS CNC MACHINING CENTERS

MM Science Journal
Five-axis CNC machine tools are indispensable for manufacturing parts with complex geometry, yet the conversion of raw kinematic measurements into reliable maintenance knowledge is still often fragmented and manual. This article presents a Python-based monitoring environment that reads R-Test export files, invokes one of three selectable machine ...
MARCIN BARSZCZ, JERZY JOZWIK, PAWEL TOMILO, DARIA SALAMACHA, KRZYSZTOF DZIEDZIC, TOMASZ WISNIEWSKI   +5 more
openaire   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Multi-axis synchronous interpolation feed rate adaptive planning with rotational tool center point function under comprehensive constraints

Advances in Mechanical Engineering, 2017
Real-time nonlinear error caused by rotation axis motion in five-axis interpolation can be compensated by rotational tool center point function.
Zhongquan Shi, Wenhua Ye, Ruijun Liang
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Sensitivity Analysis in Ball Bar Measurement of Three-Dimensional Circular Movement Equivalent to Cone-Frustum Cutting in Five-Axis Machining Centers

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2013
The present paper describes the sensitivity coefficient of measurement in the three-dimensional circular interpolation movement that is equivalent to cone-frustum cutting in five-axis machining centers with a tilting rotary table. The sensitive direction
Noriyuki KATO, Masaomi TSUTSUMI, Yu TSUCHIHASHI, Ryuta SATO, Yukitoshi IHARA   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

An attempt to relate dynamic tracking error to occurring situation based on additional rectilinear motion for five-axis machine tools

Advances in Mechanical Engineering, 2020
During five-axis CNC machining, the dynamic tracking error of the five-axis machine tool caused by imperfect servo dynamic performance is the major factor affecting the accuracy during high-speed and high-precision manufacturing.
Qicheng Ding, Jiexiong Ding, Jing Zhang, Li Du   +3 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

An integrated method for compensating and correcting nonlinear error in five-axis machining utilizing cutter contacting point data

Scientific Reports
In current five-axis computer numerical control (CNC) machining, the use of minute linear path segments as an approximation for the ideal cutter contacting (CC) point trajectory is still prevalent.
Liangji Chen, Haohao Xu, Qiang Huang, Pengcheng Wang   +3 more
doaj   +1 more source