Results 81 to 90 of about 1,241,383 (345)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Recent Progress of the Design and Engineering of Bismuth Oxyhalides for Photocatalytic Nitrogen Fixation

, 2021
Peishen Li, Shuai Gao, Qiming Liu, Peiren Ding, Yunyun Wu, Changzheng Wang, Shaobin Yu, Wen Liu, Qiang Wang, Shaowei Chen   +9 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Neuronal control of fixation and fixational eye movements

Philosophical Transactions of the Royal Society B: Biological Sciences, 2017
Ocular fixation is a dynamic process that is actively controlled by many of the same brain structures involved in the control of eye movements, including the superior colliculus, cerebellum and reticular formation.
R. Krauzlis, Laurent Goffart, Ziad M. Hafed   +2 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Salicylic and succinic acids as inducers of phytoimmunity in winter wheat for the management of powdery mildew (Blumeria graminis (DC) Speer f. sp. tritici)

BMC Plant Biology
Background Growth regulators play an important role in activating the main signal transduction pathways in response to stress, and their activity is key in the general mechanism to understanding the formation of phytoimmunity under biotic stress.
Tetiana Nyzhnyk, Marcin Kiedrzyński, Edyta Kiedrzyńska, Sergii Kots   +3 more
doaj   +1 more source

Isokinetic Muscle Strength and Knee Function in Anatomical Anterior Cruciate Ligament Reconstruction With Hamstring Autografts: A Prospective Randomized Comparative Study Between Suspensory and Expandable Femoral Fixation in Male Patients [PDF]

, 2022
Andreas Panagopoulos, Vasileios Giannatos, Georgios Moros, Dimitrios Mylonas, Antonis Kouzelis, John Gliatis   +5 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A Study of Titanium Elastic Nailing in Forearm Fractures in Elderly Patients

Journal of Orthopedic and Spine Trauma
Introduction: As operative techniques and the quality of implants are improving, surgical management of diaphyseal fractures of forearm bones in elderly patients is gaining widespread acceptance.
Ashok Sharma
doaj   +1 more source

Global patterns of marine nitrogen fixation and denitrification

Oceanographic Literature Review, 1997
A new quasi‐conservative tracer N*, defined as a linear combination of nitrate and phosphate, is proposed to investigate the distribution of nitrogen fixation and denitrification in the world oceans. Spatial patterns of N* are determined in the different
N. Gruber, J. Sarmiento
semanticscholar   +1 more source