Results 91 to 100 of about 918,085 (317)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
WMJ (Warmadewa Medical Journal)Rats are widely used in the study of embryological development of the central nervous system and its congenital disorders. Therefore, tissue fixation is very important in obtaining a good picture of the central nervous system, especially in newborn rats.
Luh Gde Evayanti +5 more
doaj +1 more source
Host Specificity and Nitrogen Fixation by Rhizobia from Native Legumes of South Dakota
, 1976 This these is concerned with a study of the study of the root nodule bacteria associate with native legumes. In the study cultural characteristics were observed along with physiological properties of the native bacterial isolates.
Fixation, Myron C.
core
, 2012 The symbiotic relationship between legumes and nitrogen fixing bacteria is critical for agriculture, as it may have profound impacts on lowering costs for farmers, on land sustainability, on soil quality, and on mitigation of greenhouse gas emissions ...
John Howieson +14 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Design and application of an arterial line set fixation device (一种动脉插件固定装置的设计与应用)
中西医结合护理Continuous monitoring of invasive blood pressure can provide real-time, accurate data monitoring for ICU patients and provide effective guidance for emergency rescue and following treatment, so flexible fixation devices are essential to ensure the ...
WANG Chenlin (王晨霖) +2 more
doaj +1 more source
Influence of pre-crop and root architecture on the mobilization of non-exchangeable NH4+
Plant, Soil and Environment, 2014 It is well established that non-exchangeable NH4+ is an important N source for plants. However, release from clay minerals only occurs when the NH4+ concentration of the mineral environment declines below a certain level.
P. Beuters, T. Eichert, H.W. Scherer
doaj +1 more source