Interplay between pleiotropy and secondary selection determines rise and fall of mutators in stress response. [PDF]
PLoS Computational Biology, 2010 Mutators are clones whose mutation rate is about two to three orders of magnitude higher than the rate of wild-type clones and their roles in adaptive evolution of asexual populations have been controversial.
Muyoung Heo, Eugene I Shakhnovich
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Invasion and effective size of graph-structured populations. [PDF]
PLoS Computational Biology, 2018 Population structure can strongly affect evolutionary dynamics. The most general way to describe population structures are graphs. An important observable on evolutionary graphs is the probability that a novel mutation spreads through the entire ...
Stefano Giaimo +2 more
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Fixation probabilities in network structured meta-populations
Scientific Reports, 2021 The effect of population structure on evolutionary dynamics is a long-lasting research topic in evolutionary ecology and population genetics. Evolutionary graph theory is a popular approach to this problem, where individuals are located on the nodes of a
Sedigheh Yagoobi, Arne Traulsen
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Explaining spatial heterogeneity in population dynamics and genetics from spatial variation in resources for a large herbivore. [PDF]
PLoS ONE, 2012 Fine-scale spatial variation in genetic relatedness and inbreeding occur across continuous distributions of several populations of vertebrates; however, the basis of observed variation is often left untested.
Adrienne L Contasti +3 more
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Limiting Genotype Frequencies of Y-Linked Genes with a Mutant Allele in a Two-Sex Population
Mathematics, 2021 A two-type two-sex branching process is considered to model the evolution of the number of carriers of an allele and its mutations of a Y-linked gene. The limiting growth rates of the different types of couples and males (depending on the allele, mutated
Miguel González +2 more
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Evolutionary dynamics in fluctuating environment
Physical Review Research, 2020 Temporal environmental variations are ubiquitous in nature, yet most of the theoretical works in population genetics and evolution assume fixed environment.
Immanuel Meyer, Nadav M. Shnerb
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Open Veterinary Science, 2021 This study aimed to investigate the genotypic distribution and population genetic parameters of the single nucleotide polymorphism (SNP) located on exon 3 at the FSHB gene in East Anatolian Red (EAR), East Anatolian Red×Holstein (EAR×H), and Zavot (Z ...
Ardicli Sena
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Understanding evolutionary and ecological dynamics using a continuum limit
Ecology and Evolution, 2021 Continuum limits in the form of stochastic differential equations are typically used in theoretical population genetics to account for genetic drift or more generally, inherent randomness of the model. In evolutionary game theory and theoretical ecology,
Peter Czuppon, Arne Traulsen
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The molecular clock of neutral evolution can be accelerated or slowed by asymmetric spatial structure. [PDF]
PLoS Computational Biology, 2015 Over time, a population acquires neutral genetic substitutions as a consequence of random drift. A famous result in population genetics asserts that the rate, K, at which these substitutions accumulate in the population coincides with the mutation rate ...
Benjamin Allen +5 more
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Reduction of a metapopulation genetic model to an effective one island model [PDF]
, 2018 We explore a model of metapopulation genetics which is based on a more ecologically motivated approach than is frequently used in population genetics. The size of the population is regulated by competition between individuals, rather than by artificially
Alan J. McKane +8 more
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