Results 41 to 50 of about 145,239 (247)
Hybrid fitness effects modify fixation probabilities of introgressed alleles
G3: Genes, Genomes, Genetics, 2022 Hybridization is a common occurrence in natural populations, and introgression is a major source of genetic variation. Despite the evolutionary importance of adaptive introgression, classical population genetics theory does not take into account hybrid ...
Aaron Pfennig, Joseph Lachance
doaj +1 more source
A tug-of-war between driver and passenger mutations in cancer and other adaptive processes [PDF]
, 2014 Cancer progression is an example of a rapid adaptive process where evolving new traits is essential for survival and requires a high mutation rate. Precancerous cells acquire a few key mutations that drive rapid population growth and carcinogenesis ...
Korolev, Kirill S. +2 more
core +2 more sources
Stochastic dynamics of adaptive trait and neutral marker driven by eco-evolutionary feedbacks [PDF]
, 2014 How the neutral diversity is affected by selection and adaptation is investigated in an eco-evolutionary framework. In our model, we study a finite population in continuous time, where each individual is characterized by a trait under selection and a ...
Billiard, Sylvain +3 more
core +3 more sources
Molecular Genetics & Genomic Medicine, 2020 Background Individual identification is one of the most important tasks in the field of forensic genetics. Insertion/Deletion (InDel) polymorphism marker has been a promising marker for individual identification. However, a part of InDel loci in commonly
Wei Cui +7 more
doaj +1 more source
Ecological Indicators, 2023 Habitat destruction and fragmentation are major factors in the destruction of genetic diversity and affect the movement behavior of the Roe deer population in the remaining habitats.
Shirin Mahmoodi +6 more
doaj +1 more source
Coalescence 2.0: a multiple branching of recent theoretical developments and their applications [PDF]
, 2014 Population genetics theory has laid the foundations for genomics analyses including the recent burst in genome scans for selection and statistical inference of past demographic events in many prokaryote, animal and plant species.
Lemaire, Christophe, Tellier, Aurelien
core +5 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Genetic Diversity and Structure of Calophyllum brasiliense Along the Santa Catarina Coast
Floresta e Ambiente, 2019 Population genetics studies can provide knowledge in support of conservation efforts for plant populations. We studied the genetic diversity and structure in nine populations of Calophyllum brasiliense from Santa Catarina state, Brazil, aiming to ...
Fernando André Loch Santos da Silva +4 more
doaj +1 more source
Fluctuating selection models and Mcdonald-Kreitman type analyses [PDF]
, 2013 It is likely that the strength of selection acting upon a mutation varies through time due to changes in the environment. However, most population genetic theory assumes that the strength of selection remains constant.
A Eyre-Walker +28 more
core +4 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source