Results 71 to 80 of about 5,625,610 (302)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Applications in Plant Sciences, 2019 Premise The genus Antennaria has a complex evolutionary history due to dioecism, excessive polyploidy, and the evolution of polyploid agamic complexes. We developed microsatellite markers from A.
Ramhari Thapa +2 more
doaj +1 more source
Revista Mexicana de Biodiversidad, 2021 The Arrayán tree (Calycolpus moritzianus) is an endemic species from northern South America and it is important for its potential in the medical and cosmetic industry.
Diego Alexander Hernández-Contreras +5 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Population Genetic Approaches to Speciation of Wild Tomatoes with Special Reference to Solanum habrochaites and S. arcanum [PDF]
, 2009 This thesis entails the results of three research projects. These have focused on the influence of diversity, demography and structure in the divergence (i.e. the speciation process) of four wild tomato species.
Merino Méndez, Carlos Gonzalo
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Exploring the Status of Population Genetics: The Role of Ecology [PDF]
, 2012 The status of population genetics has become hotly debated among biologists and philosophers of biology. Many seem to view population genetics as relatively unchanged since the Modern Synthesis and have argued that subjects such as development were left ...
Millstein, Roberta L.
core
Evolutionary Applications, 2023 Understanding the genetic targets of natural selection is one of the most challenging goals of population genetics. Some of the earliest candidate genes were identified from associations between allozyme allele frequencies and environmental variation ...
Alan Le Moan +7 more
doaj +1 more source
Rate of Fixation of Rare Variants in a Population
bioRxiv, 2017 The process of molecular evolution has been dominated by the Kimura paradigm for nearly 60 years; mutations arise at a certain rate in the population and they go to fixation with a probability given by Kimura’s classic formula, which assumes there are no
B. Khatri
semanticscholar +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source