Results 141 to 150 of about 452,734 (338)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Clinical use of a fixed-dose combination of telmisartan and indapamide in hypertension. Expert Council resolution

Российский кардиологический журнал
The aim of the expert council "First star duo of telmisartan and indapamide in the Russian Federation", dedicated to the introduction of a new fixed-dose combination of telmisartan and indapamide (modified-release tablets) into clinical practice was to ...
A. O. Konradi, F. T. Ageyev, A. S. Galyavich, Yu. A. Karpov, Zh. D. Kobalava, Yu. V. Kotovskaya, S. V. Nedogoda, A. O. Nedoshivin, O. N. Tkacheva   +8 more
doaj   +1 more source

Profile of netupitant/palonosetron (NEPA) fixed dose combination and its potential in the treatment of chemotherapy-induced nausea and vomiting (CINV)

, 2014
Rudolph M Navari Cancer Care Program, Eastern Europe, World Health Organization, Mishawaka, IN, USA; Indiana University School of Medicine, South Bend, IN, USA; South Bend Medical Services Corporation, IN, USA Abstract: Chemotherapy-induced ...
Navari RM, Navari, Rudolph M.
core   +1 more source

Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: Results from the VISIONARY Study Population in Spain

, 2022
José Javier García‐Medina, Javier Benítez del Castillo Sánchez, Iñaki Rodríguez-Agirretxe, Fernando López-López, A. Moreno-Valladares, the VISIONARY Study Group (Spain), Rafael Giménez, María Parrilla Vallejo, Alfonso Antón López, Sergio Torregrosa, Jorge Loscos   +10 more
openalex   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Long-term effect of latanoprost/timolol fixed combination in patients with glaucoma or ocular hypertension: a prospective, observational, noninterventional study

, 2010
Background: Prospective, observational studies that enroll large numbers of patients with few exclusion criteria may better reflect actual ongoing clinical experience than randomized clinical trials.
Guzy, Claudia, Miller Paul J, Oliver Schwenn, Schwenn, Oliver, Heckmann Barbara, Paul J Miller, Schwenn Oliver, Barbara Heckmann, Claudia Guzy, Miller, Paul J., Heckmann, Barbara, Guzy Claudia   +11 more
core   +1 more source

Fixed‐Dose Combination Therapy—Is It Time for This Approach to Hypertension and Dyslipidemia Management? [PDF]

, 2004
Domenic A. Sica
openalex   +1 more source

The Comparative Bioavailability of Fluticasone and Azelastine Delivered as a Single Fixed Dose Combination (MP-AzeFlu) in Comparison to Two Different Formulations of Azelastine and Fluticasone Propionate Following Intranasal Administration in Healthy Chinese Volunteers

, 2023
Wenyuan Qi, Yue Liu, Wei Xue, Kexin Li, J. Christopher Gorski, Mark Liu, Tieliang Yan, Duc Tung Nguyen, Rajesh Kumar Ramalingam   +8 more
openalex   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Safety and efficacy of fixed‐dose combination rilpivirine‐tenofovir‐emtricitabine (RPV/TDF/FTC) in treatment‐experienced patients infected with HIV‐1 [PDF]

, 2012
Müge Çevik, S Sonecha, Mark Nelson
openalex   +1 more source