Results 21 to 30 of about 8,885 (258)

Belt buckles from burials of the Second Lipetsk barrow (methods of their fabrication and reconstruction of their use) [PDF]

Archaeoastronomy and Ancient Technologies, 2015
The paper describes the fabrication method and the use of a small collection of bone buckles discovered along with the luxurious grave goods from the uncommon burials of the Don-Volga Abashevo culture Second Lipetsk barrow (excavation of 2011).
Usachuk, A.N.
doaj   +1 more source

THE TRIBOLOGICAL BEHAVIOR OF POLYETHYLENE FILLED BY NANOPOWDER OF ALUMINUM OXIDE [PDF]

Journal of the Egyptian Society of Tribology, 2016
The present study investigates the abrasive wear of surfaces subjected to abrasive contaminants. Polyethylene (PE) filled with nanoparticles of aluminum oxide were used as coating for steel specimens.  Their effect on wear of moving surfaces contaminated
A. A. Ezzat, M. O. Mousa, W. Y. Ali
doaj   +1 more source

Effect of lapping temperature on performance of hydrophilic fixed abrasive pad

Jin'gangshi yu moliao moju gongcheng, 2020
The rise of lapping temperature causes a change in the modulus of the resin matrix, thereby affecting the processing performance of the hydrophilic fixed abrasive pad.The transient temperature field of hydrophilic fixed abrasive pad at different slurry ...
ZHANG Jiaqian, SHEN Gongming, TANG Chao, ZHU Yongwei   +3 more
doaj  

Research progress on abrasive geometry modeling and application

Jin'gangshi yu moliao moju gongcheng
SignificanceAbrasives are recognized as indispensable in precision machining, and their role in processing critical components has been firmly established.
Fei PENG, Yanbin ZHANG, Rukang ZHANG, Xin CUI, Peiming XU, Lan DONG, Xiaotian ZHANG, Xuelei SONG, Changhe LI   +8 more
doaj   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Advances in modeling of fixed-abrasive processes

CIRP Annals
Published by CIRP ...
Krajnik, Peter, Wegener, Konrad, Bergs, Thomas, Shih, Albert J.   +3 more
openaire   +3 more sources