Results 61 to 70 of about 687,321 (307)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Comparative Survey on the Records of Fixed Assets of Companies and Public Institutions [PDF]
This paper deals by way of comparison with the theoretical and practical methods to record the output and input of tangible fixed assets (non-current assets) in and from the patrimony of companies, on the one side and of public institutions, on the other
Ecobici, Nicolae
core +1 more source
Ipteks Prosedur Penilaian Aset Tetap pada Kantor Pelayanan Kekayaan Negara dan Lelang (Kpknl) Manado [PDF]
, 2018 Fixed assets are tangible assets to be owned or used in the production, supply of goods or services. Aim to administer and be used for more than one period.
Maruf, J. M. (Juniarti) +2 more
core
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
ROLE OF MAIN ACTIVITIES IN FORMATION OF THE CAPITAL OF AN ENTERPRISE, THEIR EVALUATION AND CONTROL
Фінансово-кредитна діяльність: проблеми теорії та практики, 2019 The article deals with the problem of valuation and control of non-current assets, in particular of fixed assets, determination of their role in the formation of the enterprise’s own capital, their correct and reliable evaluation at the enterprise.
O. H. Chyrva +3 more
doaj +1 more source
Does the Company's Scale, Fixed Asset Intensity and Operating Cash Flow Affect Asset Revaluation?
Jurnal Analisis Bisnis Ekonomi, 2020 Fixed assets that are measured using cost may have lost their relevance because they do not reflect the real situation. This study aims to analyze the factors that influence the company to revaluate its fixed assets. The sample of this study consisted of
Rr. Tjahjaning Poerwati +3 more
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Food marketing cooperatives of Crete: A financial assessment within the EU context [PDF]
In this paper an estimate is made concerning the correlation between the prosperity and viability of food enterprises and the volume of fixed assets. The amount of investment in fixed assets refers to the volume of the food cooperative activities. Hence,
Alexakis, Dimitrios +3 more
core +1 more source