Results 91 to 100 of about 1,967,755 (312)

RESPONSE COST AND FIXED‐RATIO PERFORMANCE [PDF]

open access: yesJournal of the Experimental Analysis of Behavior, 1964
The effects of several conditions of response cost (response‐produced point loss) upon FR 50 performance maintained by 100‐point reinforcements were investigated. Post‐reinforcement pauses did not appear under no‐cost (no points deducted per response) conditions.
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Enforcement Costs and the Optimal Magnitude and Probability of Fines [PDF]

open access: yes
Some of the costs of enforcing laws are fixed" - - in the sense that they do not depend on the number of individuals who commit harmful acts- -while other costs are "variable"- - they rise with the number of such individuals.
A. Mitchell Polinsky, Steven Shavell
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Non-Tariff Barriers, Market Access and Trade [PDF]

open access: yes
This paper analyses the effects of non-tariff barriers, in terms of both variable and fixed export costs, on trade structure. The relationship between fixed and variable trade costs determines whether international trade emerges.
Mathä, Thomas
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Study of Operational and Maintenance Costs for Public Bus Transport

open access: yesJurnal Teknik Industri: Jurnal Hasil Penelitian dan Karya Ilmiah dalam Bidang Teknik Industri
Public transportation is a means of transportation for travelling and carrying out daily activities, and it has become one of the community's transportation needs.
Catra Editya Kusuma, Fajar Dewantoro
doaj   +1 more source

Radar Detectors, Fixed and Variable Costs of Crime [PDF]

open access: yes
Raising the sanction will always reduce the utility of the criminal. However, raising the sanction will not always lead to less crime, and may lead to more crime.
Timothy Stanley
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Internal audit of costs on fixed assets repair

open access: yesПроблеми теорії та методології бухгалтерського обліку, контролю і аналізу, 2016
The article focuses on the approaches to the process and methods of expenditure audit on repair and modernization of fixed assets and the author considers that there is no single approach to understanding the issue.
M.Yu. Samchyk
doaj  

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