Results 71 to 80 of about 3,216,879 (306)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Fixed Costs and Long-Lived Investments [PDF]
Neoclassical investment models predict that firms should make frequent, small adjustments to their capital stocks. Microeconomic evidence, however, shows just the opposite -- firms make infrequent, large adjustments to their capital stocks.
Christopher L. House
core
Assets: Jurnal Akuntansi dan Pendidikan, 2012 This research aims to analyze the estimated Cost-Volume-Profit (CVP) in association with the Profit Planning at Tlogo Mas Hotel Sarangan. Analytical techniques used in this study were: (1) Classify all costs incurred in the variable costs (variable costs)
Satrijo Budi Wibowo
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
An irreversible investment model with a stochastic production capacity and fixed plus proportional adjustment costs [PDF]
This paper studies the problem of a company which expands its stochastic production capacity in irreversible investments by purchasing capital and faces both fixed and proportional costs.
Yiannis Kamarianakis +1 more
core
Supplier Fixed Costs and Retail Market Monopolization [PDF]
, 2014 Considering a vertical structure with perfectly competitive upstream firms that deliver a homogenous good to a differentiated retail duopoly, we show that upstream fixed costs may help to monopolize the downstream market.
Caprice, Stéphane +2 more
core +2 more sources
Journal of Algorithms & Computational Technology, 2015 This paper presents a new variant of the capacitated multi-source Weber problem that introduces fixed costs for opening facilities. Three types of fixed costs are considered and experimented upon.
Martino Luis, Said Salhi, Gábor Nagy
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
, 2017 The Fixperts film archive hosts the documentation aspect of design based Fixperts projects from participants all around the world. It is managed though Youtube and disseminated through a dedicated online platform on the FixEd website.
Charny, Daniel, FixEd
core
Methodology of Day-To-Day Ship Costs Assessment
Promet (Zagreb), 2006 The paper presents a methodology of assessing the day-to-day fixed costs of maritime cargo ships. The authoress refersthe reader to factors that affect the amount affixed daily costsand the day-to-day voyage costs of ships.
Milojka Počuča
doaj +1 more source