Results 61 to 70 of about 3,216,879 (306)
Fixed adjustment costs and aggregate fluctuations [PDF]
Journal of Monetary Economics, 2019 This paper studies the analytics of a canonical model of …xed adjustment costs in the presence of idiosyncratic productivity shocks. We provide a novel analytical characterization of the steady state and dynamics of aggregate outcomes implied by the model. The dynamics are shown to have an intuitive partial-adjustment representation.
Ryan Michaels, Michael Elsby
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Predicting Operating Income via a Generalized Operating-Leverage Model
International Journal of Financial StudiesWe propose a generalized, practitioner-oriented operating-leverage model for predicting operating income using net sales, cost of sales, depreciation, and SG&A.
Sherwood Lane Lambert +2 more
doaj +1 more source
Individual Travel Cost Method and Flow Fixed Costs [PDF]
, 2002 The paper proposes an approach for evaluating the effect of flow fixed costs on the evaluation of environmental benefits with travel cost method. On a full annual perspective when recreational users incur relevant annual direct fixed expenses, their behaviour could be influenced by them. The approach introduces a) the notion of the minimal number of
DEFRANCESCO, EDI, ROSATO P.
openaire +4 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Variable Costs, Fixed Costs and Entry Deterrence
, 2015 R&D is used by firms to reduce different types of costs including variable production costs and fixed production costs. An incumbent monopolist and a potential entrant can adopt R&D to reduce their costs with bidirectional technological spillovers ...
Chen, Xiaotang
core +2 more sources
ProceedingsThe aim of this research is to estimate the fixed costs of the maintenance of draft horses in a low-input farm. Research has revealed that in the investigated case, the fixed costs of maintenance of three draft mares were EUR 5115.39 annually, with human
Ranko Gantner +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2020 FixEd is an organsiation dedicated to ensuring more people are more capable of applying creativity to change. The FixEd online platform is represented by a short video tour.
Halligan, Dee, Charny, Daniel
core
CONSIDERATIONS ON THE RATIONAL IMPUTATION OF THE FIXED EXPENSES [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2009 In this material we tried to address some issues relating to the rational allocation of fixed expenses, which is the elimination of complete calculation of costs of products, works or services variations in the incidence of activity.
Maria SANDU , Rodica BADIŢĂ
doaj