Results 101 to 110 of about 560,761 (277)

Nested Pseudo-likelihood Estimation and Bootstrap-based Inference for Structural Discrete Markov Decision Models [PDF]

open access: yes
This paper analyzes the higher-order properties of nested pseudo-likelihood (NPL) estimators and their practical implementation for parametric discrete Markov decision models in which the probability distribution is defined as a fixed point. We propose a
Hiroyuki Kasahara, Katsumi Shimotsu
core  

Fixed Point Iterations for Certain Nonlinear Mappings

open access: yesJournal of Mathematical Analysis and Applications, 1994
The author generalizes a recent existence and convergence theorem by \textit{J. Schu} [J. Math. Anal. Appl. 158, No. 2, 407-413 (1991; Zbl 0734.47036)] from Hilbert spaces to uniformly convex spaces.
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Data Dependence for Ishikawa Iteration When Dealing with Contractive-Like Operators

open access: yesFixed Point Theory and Applications, 2008
We prove a convergence result and a data dependence for Ishikawa iteration when applied to contraction-like operators. An example is given, in which instead of computing the fixed point of an operator, we approximate the operator with a contractive-like ...
Teodor Grosan, Ş. M. Şoltuz
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

A Modified Mann Iteration by Boundary Point Method for Finding Minimum-Norm Fixed Point of Nonexpansive Mappings

open access: yesAbstract and Applied Analysis, 2013
Let H be a real Hilbert space and C⊂H a closed convex subset. Let T:C→C be a nonexpansive mapping with the nonempty set of fixed points Fix(T). Kim and Xu (2005) introduced a modified Mann iteration x0=x∈C, yn=αnxn+(1−αn)Txn, xn+1=βnu+(1−βn)yn, where u∈C
Songnian He, Wenlong Zhu
doaj   +1 more source

Fitness Conditions for fixed Point Iteration

open access: yesDAIMI Report Series, 1992
This paper provides a link between the formulation of static program analyses using the framework of abstract interpretation (popular for functional languages) and using the more classical framework of data flow analysis (popular for imperative languages).
Flemming Nielson, Hanne Riis Nielson
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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