Results 71 to 80 of about 4,288,634 (382)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

New Existence Results for Fixed Point Problem and Minimization Problem in Compact Metric Spaces

Abstract and Applied Analysis, 2014
We first present some new existence theorems for fixed point problem and minimization problem in compact metric spaces without assuming that mappings possess convexity property.
Weng-Seng Heng, Wei-Shih Du, Chi-Lin Yen
doaj   +1 more source

Density-potential mappings in quantum dynamics

, 2012
In a recent letter [Europhys. Lett. 95, 13001 (2011)] the question of whether the density of a time-dependent quantum system determines its external potential was reformulated as a fixed point problem.
A. Bielecki, A. L. Fetter, A. Zettl, C. A. Ullrich, D. H. Griffel, E. Engel, K. J. H. Giesbertz, L. C. Evans, M. Bonitz, M. Penz, M. Ruggenthaler, Ph. Blanchard, R. M. Dreizler, R. van Leeuwen, W. A. Light, W. Walter   +15 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Iterative Algorithms for the Split Problem and Its Convergence Analysis

Abstract and Applied Analysis, 2014
Now, it is known that the split common fixed point problem is a generalization of the split feasibility problem and of the convex feasibility problem. In this paper, the split common fixed point problem associated with the pseudocontractions is studied ...
Zhangsong Yao, Arif Rafiq, Shin Min Kang, Li-Jun Zhu   +3 more
doaj   +1 more source

Discussion on the fixed point problems with constraint inequalities

Journal of Inequalities and Applications, 2018
In this paper, we introduce the concept of comparable complete metric spaces and consider some fixed point theorems for mappings in the setting of incomplete metric spaces. We obtain the results of Ansari et al. [J. Fixed Point Theory Appl. 20:26, 2018] with weaker conditions. Moreover, we provide some corollaries and examples show that our main result
Badr Alqahtani, Rahmatollah Lashkaripour, Erdal Karapınar, Javad Hamzehnejadi   +3 more
openaire   +3 more sources

On solving the split generalized equilibrium problem and the fixed point problem for a countable family of nonexpansive multivalued mappings

, 2018
We consider the split generalized equilibrium problem and the fixed point problem for a countable family of nonexpansive multivalued mappings in real Hilbert spaces.
Withun Phuengrattana, Kritsada Lerkchaiyaphum   +1 more
semanticscholar   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

Critical Theory of Non-Fermi Liquid Fixed Point in Multipolar Kondo Problem

Physical Review X, 2020
When the ground state of a localized ion is a non-Kramers doublet, such localized ions may carry multipolar moments. For example, Pr^{3+} ions in a cubic environment would possess quadrupolar and octupolar, but no magnetic dipole, moments.
Adarsh S. Patri, Yong Baek Kim
doaj   +1 more source

Modified Krasnoselski–Mann iterative method for hierarchical fixed point problem and split mixed equilibrium problem

Journal of Inequalities and Applications, 2020
In this paper, we introduce a modified Krasnoselski–Mann type iterative method for capturing a common solution of a split mixed equilibrium problem and a hierarchical fixed point problem of a finite collection of k-strictly pseudocontractive nonself ...
Jong Kyu Kim, Prashanta Majee
doaj   +1 more source