Results 71 to 80 of about 4,176,488 (382)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

The Split Equality Fixed-Point Problem and Its Applications

Axioms
It is generally known that in order to solve the split equality fixed-point problem (SEFPP), it is necessary to compute the norm of bounded and linear operators, which is a challenging task in real life.
Lawan Bulama Mohammed, Adem Kilicman
doaj   +1 more source

An inertial parallel algorithm for a finite family of G-nonexpansive mappings with application to the diffusion problem

Advances in Difference Equations, 2021
For finding a common fixed point of a finite family of G-nonexpansive mappings, we implement a new parallel algorithm based on the Ishikawa iteration process with the inertial technique. We obtain the weak convergence theorem of this algorithm in Hilbert
Phakdi Charoensawan, Damrongsak Yambangwai, Watcharaporn Cholamjiak, Raweerote Suparatulatorn   +3 more
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Fixed gate point location problems

TOP, 2020
Given a metric space with a set of given facilities, location theory asks to place a new facility which minimizes the distances to the given ones. Many results for a variety of problems with norms or metrics as distances are known in the space $${\mathbb {R}}^n$$
openaire   +3 more sources

On Fixed Point and Almost Fixed Point Problems of Lower Semicontinuous Type Multivalued Mappings

Acta Mathematica Sinica, English Series, 2005
The authors obtain almost fixed point theorems and fixed point theorems for lower semicontinuous type multivalued mappings in metrizable H-spaces. As an application, they obtain a nonempty intersection theorem for a multivalued mapping on a compact H-convex space. The main results are good variants and generalizations of the almost fixed point theorems
Liang Yu Luan, Xian Wu
openaire   +4 more sources

Third Order Renormalization Group applied to the attractive one-dimensional Fermi Gas

, 2000
We consider a Callan-Symanzik and a Wilson Renormalization Group approach to the infrared problem for interacting fermions in one dimension with backscattering.
A. I. Larkin, A. Luther, A. Luther, A. Theumann, C. S. Ting, C. S. Ting, D. C. Mattis, D. C. Mattis, D. C. Mattis, D. C. Mattis, E. H. Rezayi, F. Bonetto, F. Bonetto, F. Bonetto, F. Bonetto, F. D. M. Haldane, F. D. M. Haldane, G. Benfatto, G. Benfatto, G. Benfatto, G. Benfatto, G. Gallavotti, G. Gentile, I. Affleck, I. E. Dyaloshinskiĭ, J. M. Luttinger, J. Sòlyom, J. Sòlyom, K. D. Schotte, K. Wilson, N. Menyárd, N. Menyárd, Paolo Carta, R. Heidenreich, S. T. Chui, T. Bell   +35 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Discussion on the fixed point problems with constraint inequalities

Journal of Inequalities and Applications, 2018
In this paper, we introduce the concept of comparable complete metric spaces and consider some fixed point theorems for mappings in the setting of incomplete metric spaces. We obtain the results of Ansari et al. [J. Fixed Point Theory Appl. 20:26, 2018] with weaker conditions. Moreover, we provide some corollaries and examples show that our main result
Badr Alqahtani, Rahmatollah Lashkaripour, Erdal Karapınar, Javad Hamzehnejadi   +3 more
openaire   +4 more sources

Iterative Algorithms for the Split Problem and Its Convergence Analysis

Abstract and Applied Analysis, 2014
Now, it is known that the split common fixed point problem is a generalization of the split feasibility problem and of the convex feasibility problem. In this paper, the split common fixed point problem associated with the pseudocontractions is studied ...
Zhangsong Yao, Arif Rafiq, Shin Min Kang, Li-Jun Zhu   +3 more
doaj   +1 more source