Results 81 to 90 of about 425,800 (302)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Future broadband access network challenges [PDF]

open access: yes, 2010
Copyright @ 2010 IEEEThe optical and wireless communication systems convergence will activate the potential capacity of photonic technology for providing the expected growth in interactive video, voice communication and data traffic services that are ...
Abdollahi, SR   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Modeling and Simulation of Three-phase PWM Rectifier Based on Fixed Switching Frequency Control Strategy

open access: yesGong-kuang zidonghua, 2010
The paper introduced a mathematical model of three-phase PWM rectifier, analyzed principle of fixed switching frequency control strategy,built control structure of PWM rectifier based on inner current loop and outer voltage loop the simulated the fixed ...
WANG Xian-bo   +3 more
doaj  

Two-output Class E Isolated dc-dc Converter at 5 MHz Switching Frequency [PDF]

open access: yes, 2010
This paper presents a two output class-E isolated dcdc converter that regulates the output voltages at fixed switching frequency. The converter is simulated at operating frequency of 5 MHz.
Alou Cervera, Pedro   +5 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

A Fixed Switching Frequency Model Predictive Control Strategy With Reactive Power Handling Capability and Improved Current Tracking for Vienna Rectifiers

open access: yesIEEE Open Journal of Power Electronics
Vienna rectifiers are widely used for high power density AC–DC conversion in applications such as electric vehicle chargers, power supplies, and industrial front-end rectifiers.
Abdul Nazer P, Harish Sudhakaran Nair
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

High-Frequency Resonant SEPIC Converter With Wide Input and Output Voltage Ranges [PDF]

open access: yes, 2011
This paper presents a resonant single-ended-primary-inductor-converter (SEPIC) converter and control method suitable for high frequency (HF) and very high frequency (VHF) dc-dc power conversion.
Davis, Seth M.   +5 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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