Results 91 to 100 of about 7,647,352 (298)
Searching for the Lightest Neutralino at Fixed Target Experiments
4 pages, 6 figs, phenomenological ...
Borissov, L., Conrad, J., Shaevitz, M.
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The nucleon structure from fixed target experiments [PDF]
A review is presented of recent experimental results on the internal structure of protons and neutrons, with emphasis on deep inelastic electron, muon, and neutrino scattering. The topics discussed include new results on unpolarized nucleon structure functions, tests of the Quark‐Parton Model, determinations of the strong coupling constant and the ...
openaire +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
First observation and study of the K ± → π 0 π 0 μ ± ν decay
The NA48/2 experiment at CERN reports the first observation of the K ± → π 0 π 0 μ ± ν decay based on a sample of 2437 candidates with 15% background contamination collected in 2003–2004.
The NA48/2 collaboration +123 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
NO LESS: Novel Opportunities for Light Exotic Searches at the SPS
A powerful way to test models with feebly interacting particles in the MeV to GeV mass range is through proton beam-dump experiments. In this paper, we compare the current sensitivity of CERN’s NA62 experiment running in beam-dump mode with that of a ...
Babette Döbrich +4 more
doaj +1 more source
In recent years, a number of intensity frontier experiments have been proposed to search for feebly interacting particles with masses in the GeV range.
Kyrylo Bondarenko +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

