Results 81 to 90 of about 7,647,352 (298)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Review of calorimetry in Fermilab fixed-target experiments [PDF]

open access: yes, 1995
The fixed-target program at Fermilab comprises as many as thirteen simultaneous experiments in ten separate beamlines using beams of primary protons, pions, kaons, electrons, neutrinos, and muons.
Crisler, M. B.
core  

Search for a new 17 MeV resonance via e + e − annihilation with the PADME experiment

open access: yesJournal of High Energy Physics
The PADME Experiment at the Frascati DAΦNE linear accelerator has searched for a hypothetical particle with mass around 17 MeV, commonly referred to as the X17, using a positron beam incident on a fixed target.
The PADME collaboration   +27 more
doaj   +1 more source

An investigation of the very rare K + → π + ν ν ¯ $$ {K}^{+}\to {\pi}^{+}\nu \overline{\nu} $$ decay

open access: yesJournal of High Energy Physics, 2020
The NA62 experiment reports an investigation of the K + → π + ν ν ¯ $$ {K}^{+}\to {\pi}^{+}\nu \overline{\nu} $$ mode from a sample of K + decays collected in 2017 at the CERN SPS. The experiment has achieved a single event sensitivity of (0.389 ± 0.024)
The NA62 collaboration   +200 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

New Fixed-Target Experiments to Search for Dark Gauge Forces [PDF]

open access: yes, 2010
Fixed-target experiments are ideally suited for discovering new MeV-GeV mass U(1) gauge bosons through their kinetic mixing with the photon. In this paper, we identify the production and decay properties of new light gauge bosons that dictate fixed ...
Essig, Rouven   +3 more
core  

Strangeness production in s NN $$ \sqrt{s_{\textrm{NN}}} $$ = 3 GeV Au+Au collisions at RHIC

open access: yesJournal of High Energy Physics
We report multi-differential measurements of strange hadron production ranging from mid- to target-rapidity in Au+Au collisions at a center-of-momentum energy per nucleon pair of s NN $$ \sqrt{s_{\textrm{NN}}} $$ = 3 GeV with the STAR experiment at RHIC.
The STAR collaboration   +362 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Fixperts films archive

open access: yes, 2017
The Fixperts film archive hosts the documentation aspect of design based Fixperts projects from participants all around the world. It is managed though Youtube and disseminated through a dedicated online platform on the FixEd website.
Charny, Daniel, FixEd
core  

Sensitivity to kaon decays to ALPs at fixed target experiments

open access: yesPhysical Review D
We study the sensitivity of fixed target experiments to hadronically coupled axionlike particles (ALPs) produced in kaon decays, with a particular emphasis on current and upcoming Short-Baseline Neutrino (SBN) experiments. We demonstrate that below the kaon decay mass threshold (
Berger, Joshua, Putnam, Gray
openaire   +3 more sources

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