Results 171 to 179 of about 2,034 (179)

A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD+-SIRT1 signaling

Biogerontology, 2015
Shu-Lan Yeh, Nae-Cherng Yang, Miao Lin Hu   +2 more
exaly  

FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells

Biochemical and Biophysical Research Communications, 2015
Antje Garten, Melanie Penke, Thomas S. Weiss   +2 more
exaly  

Genomic and tumor biological aspects of the anticancer nicotinamide phosphoribosyltransferase inhibitor FK866 in resistant human colorectal cancer cells

Genomics, 2019
Akira Sato, Yoko Ogino
exaly  

On-Target Effect of FK866, a Nicotinamide Phosphoribosyl Transferase Inhibitor, by Apoptosis-Mediated Death in Chronic Lymphocytic Leukemia Cells

Clinical Cancer Research, 2014
James B Johnston, Eric D J Bouchard, Versha Banerji   +2 more
exaly  

Synthesis of a C-Iminoribofuranoside Analog of the Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitor FK866

Helvetica Chimica Acta, 2012
exaly  

FK866 attenuates receptor activator of nuclear factor kappa-B ligand-induced osteoclastogenesis

International Journal of Oral Biology
Chang Youp Ok, Hye-Ock Jang, Moon-Kyoung Bae, Soo-Kyung Bae   +3 more
openaire   +1 more source

Genome-wide investigation of FK866-induced effects in Jurkat cells

2013
Zucal, C, D'Agostino, V, Tebaldi, T, Bruzzone, S, Quattrone, A, Nencioni, A, Provenzani, A   +6 more
openaire   +1 more source

Nicotinic acid phosphoribosyltransferase is overexpressed in solid tumors and regulates cancer cell metabolism and susceptibility to FK866

2017
Piacente, F, Caffa, I, Sociali, G, Bruzzone, S, Ballestrero, A, Odetti, P, Ravera, S, Passalacqua, M, Cea, M, Nencioni, A   +9 more
openaire   +1 more source

“Synthesis and biological evaluation of triazole analogues of FK866, a potent inhibitor of human Nicotinamide Phosphoribosyltransferase”

2008
GALLI, Ubaldina, S. Maffeo, TRON, Gian Cesare, E. Ercolano, R. A. Billington   +4 more
openaire   +1 more source