Results 101 to 110 of about 93,555 (212)
Engineered FKBP** permits regulation of PTEN function in the zebrafish.
(A) The migration and growth of stable FKBP**-PTEN expressing U87MG cell clones injected into zebrafish embryos can be inhibited by Shld1. Prior to microinjection into the perivitelline cavity of 2 days post fertilization (dpf) zebrafish embryos, cells ...
Karen Liu (778448) +7 more
core +1 more source
Non-canonical binding to the FKBP domain. a Binding of the T1 peptide to the FKBP domain in the 1.6-Å structure of TtSlyDFL:T1. The model is colored as in Fig. 5, and the 1 σ 2Fo-Fc electron density map is shown in gray around the peptide and key binding
Kristofer Modig (1273527) +6 more
core +1 more source
A Monte Carlo docking procedure that combines random displacements of the substrate and protein side chains with minimization of the enzyme substrate complex is described and applied to finding the binding mode of the blocked tetrapeptide N-acetyl-Leu ...
Stefan Fischer +2 more
core
Phylogenetic Modeling of the Histone Deacetylase 2-FK506 Binding (HD2-FKBP) Protein Family
Histone deacetylase 2-FKS06 binding proteins share two well-defined structural domains: the HD2 domain and the FKS06-binding domain. The evolutionary history of this protein family remains largely unknown.
Gifford, Benjamin
core
The aryl hydrocarbon receptor-interacting protein (AIP) has been predicted to consist of an N-terminal FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) domain and a C-terminal tetratricopeptide repeat (TPR) domain, as typically found in FK506 ...
Anne-Katrin Paschke (45043) +7 more
core +1 more source
A novel protein, belonging to the yeast family of FKBPs (FK-binding proteins), FKBP-70, was isolated from Saccharomyces cerevisiae by its interaction with the immunosuppressive agent FK-520. Its structural gene, FPR3, was cloned and the protein expressed
N.Rao Movva +11 more
core +1 more source
Harvy Mauricio Velasco,1,2 Jessica L Morales2 1Master of Human Genetics, National University of Colombia and Geneticist in Central Military Hospital, Bogotá DC, Colombia; 2Faculty of Medicine, Universidad Nacional de Colombia, Bogotá DC ...
Velasco HM, Morales JL
doaj
Background Oxidative stress arises from disrupted equilibrium between reactive oxygen species generation and cellular antioxidant capacity, serving as a pivotal mechanism in inflammatory pathology, particularly osteoarthritis development. The progression
Liangkun Huang +6 more
doaj +1 more source

