Results 111 to 120 of about 98,169 (229)

Relationship of FKBP to PKCI-2 [PDF]

Nature, 1991
M W, Albers, J, Liu, S L, Schreiber
openaire   +2 more sources

Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy. [PDF]

, 2019
Increased adrenergic tone resulting from cardiovascular stress leads to development of heart failure, in part, through chronic stimulation of β1 adrenergic receptors (βARs) on cardiac myocytes.
Irannejad, Roshanak, Nash, Craig A, Smrcka, Alan V, Wei, Wenhui   +3 more
core   +1 more source

The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13.

Journal of Biological Chemistry, 1992
Extracts from human Jurkat cells or from calf thymus contain a 60-kDa protein that is bound to immobilized FK506. As expected, the NH2-terminal sequences of the 60-kDa protein from these two species were found to be nearly the same. We were surprised to discover, however, that the sequence of the human protein was identical to that of Hsp56, a heat ...
A W, Yem, A G, Tomasselli, R L, Heinrikson, H, Zurcher-Neely, V A, Ruff, R A, Johnson, M R, Deibel   +6 more
openaire   +2 more sources

Longitudinal studies of trauma in police officers

European Journal of Psychotraumatology, 2012
Background : Results will be presented on a prospective longitudinal study of risk and resilience for post-traumatic stress disorder (PTSD) symptoms in 400 police academy recruits, assessed during academy training and followed during the first 7 years of
Charles Marmar
doaj   +1 more source

On the calculation of 3 J αβ-coupling constants for side chains in proteins [PDF]

, 2018
Structural knowledge about proteins is mainly derived from values of observables, measurable in NMR spectroscopic or X-ray diffraction experiments, i.e.
Allison, Jane, Eichenberger, Andreas, Steiner, Denise, van Gunsteren, Wilfred   +3 more
core  

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA.

, 2014
The regulated loading of the replicative helicase minichromosome maintenance proteins 2–7 (MCM2–7) onto replication origins is a prerequisite for replication fork establishment and genomic stability.
Fernández-Cid, A, Herrera, MC, Li, H, Riera, A, Samel, SA, Speck, C, Sun, J, Tognetti, S   +7 more
core   +1 more source

A receptor endocitózis inozitol lipid szabályozásának molekuláris alapjai = Molecular basis of inositol lipid regulation of receptor endocytosis [PDF]

, 2011
1. A plazmamembrán (PM) foszfatidilinozitol 4,5-biszfoszfát (PtdInsP2) szintjének csökkentésére kifejlesztett, rapamycin függő heterodimerizációs rendszer módosításával megoldottuk a transz-Golgi foszfatidilinozitol 4-foszfát mennyiségének akut ...
Balla, András, Várnai, Péter
core  

An optimized, broadly applicable piggyBac transposon induction system [PDF]

, 2017
Chen, Xuhua, Mayhew, David, Mitra, Robi David, Qi, Zongtai, Sankararaman, Sumithra, Wilkinson, Michael Nathaniel   +5 more
core   +2 more sources

Novel mutation of FKBP10 in a pediatric patient with osteogenesis imperfecta type XI identified by clinical exome sequencing

The Application of Clinical Genetics, 2017
Harvy Mauricio Velasco,1,2 Jessica L Morales2 1Master of Human Genetics, National University of Colombia and Geneticist in Central Military Hospital, Bogotá DC, Colombia; 2Faculty of Medicine, Universidad Nacional de Colombia, Bogotá DC ...
Velasco HM, Morales JL
doaj  

Psychological stress-induced systemic corticosterone directly sabotages intestinal stem cells and exacerbates colitis

Cell Discovery
Psychological stress has profound impacts on the gastrointestinal tract via the brain‒gut axis. However, its effects on intestinal stem cells (ISCs) and the resulting implication for intestinal homeostasis remain poorly understood.
Xiaole Sheng, Lanfei Jin, Zhengrong Yao, Jiaji Gu, Longtao Zhu, Andi Huang, Junxuan Peng, Xin Xu, Xiaolong Ge, Wei Zhou, Jinghao Sheng, Zhengping Xu, Rongpan Bai   +12 more
doaj   +1 more source