Adhesives for orthodontic bracket bonding [PDF]
The advent of acid etching, introduced by Buonocore in 1955, brought the possibility of bonding between the bracket base and enamel, contributing to more esthetic and conservative orthodontics.
Ana Cláudia da Silva Araújo +4 more
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Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
EFECTIVIDAD TOPICA DEL HIDROXIDO DE ALUMINIO EN EL TRATAMIENTO DE CARIES DENTAL INCIPIENTE DE INCISIVOS PERMANENTES, EN ESCOLARES DE 9 A 12 AÑOS DE EDAD DE LA I.E.P AUGUSTO CARDICH, HUANUCO 2017 [PDF]
Determinar la efectividad tópica del Hidróxido de Aluminio en el tratamiento de la caries dental incipiente de incisivos permanentes, en escolares de 09 a 12 años, Huánuco, 2015. Métodos.
Requez Robles, Wilder
core +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Corrosão e ligas metálicas usadas em mini implantes para ancoragem ortodôntica temporária: uma revisão integrativa da literatura [PDF]
O objetivo deste trabalho foi apresentar uma compilação de dados reportados na literatura sobre à resistência à corrosão de ligas metálicas utilizadas para produzir mini-implantes na ancoragem ortodôntica temporária.
Milani, Rodrigo Alexandre
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A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Saúde baseada em evidências [PDF]
Você terá acesso aos principais aspectos conceituais e operacionais da “saúde baseada em evidências”, de maneira a informar os profissionais da área da saúde acerca da utilização das melhores evidências científicas disponíveis para a prática profissional
Peres, Marco Aurélio +1 more
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HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source

