Results 31 to 40 of about 316,716 (242)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Revista Facultad de Odontología Universidad de Antioquia, 1992 Con el propósito de determinar presencia de flúor sistémico después de la aplicación de los enjuagues con fluoruro de sodio al 2% en niños en edad escolar, se hizo análisis de flúor en la orina de dos grupos de niño: experimental y control.
Fanny Lucía Yepes Delgado +2 more
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Ten years of external control of the fluoride level in public drinking water provided by Brazilian cities, Brazil, 1996-2006 [PDF]
RGO: Revista Gaúcha de Odontologia, 2008 Objective: To evaluate the program of external control of water fluoridation performed in the periods between 1996 and 2006 by ten cities: eight in the State of São Paulo, one in Minas Gerais and another in the State of Ceará.
Jaime Aparecido Cury +4 more
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Vigilância da concentração de flúor nas águas de abastecimento público na cidade de Passo Fundo - RS
Cadernos de Saúde Coletiva, 2016 Resumo Introdução O flúor possui eficácia no combate e na prevenção à cárie dentária, o que justifica sua adição na água de abastecimento público, no sal, em géis, soluções para bochechos, vernizes, dentifrícios e materiais restauradores.
Carla Simone de Brito +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Quantitative assessment of antibody internalization with novel monoclonal antibodies against Alexa fluorophores. [PDF]
PLoS ONE, 2015 Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization.
Sindy Liao-Chan +8 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Ciencia Veterinaria, 2017 La provincia de La Pampa (Argentina) se caracteriza por presentar en sus aguas subterráneas alta concentración de arsénico y flúor. En este trabajo, se determinó la concentración de flúor y arsénico en el agua de red que llega a los habitantes de la ...
Alberto Oscar Pariani +7 more
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