Results 241 to 250 of about 996,228 (285)

O-GlcNAcylation of XRCC4 controls its stability and confers resistance to DNA double-strand break damage in cancer cells. [PDF]

Cell Death Dis
Ko JY, Kweon TH, Jung H, Kang J, Kim Y, Kim YJ, Shin D, Yang SW, Lee MM, Hong JY, Lim JM, Yi EC, Cho JW, Yang WH.   +13 more
europepmc   +1 more source

EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets

Advanced Science, EarlyView.
Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang, Fujun Hou, Xunuo Jin, Yuhang Xiang, Dongli Pan   +4 more
wiley   +1 more source

Recovery of α-L-fucosidase in fucosidosis nonsense variants by readthrough stimulation and release factor degradation.

Dis Model Mech
Bäumges H, Lebeda D, Deppe P, Ilse MB, Thoms S, Lübke T.   +5 more
europepmc   +1 more source

Candidate Interaction Partners of Calpain-5 Suggest Clues to Its Involvement in Neovascular Inflammatory Vitreoretinopathy. [PDF]

Cells
Gal J, Bondada V, Crasta R, Croall DE, Vary CP, Geddes JW.   +5 more
europepmc   +1 more source

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Advanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo   +7 more
wiley   +1 more source

SARS-CoV-2 nonstructural protein 1 suppresses host transcription by reducing RNA polymerase II levels. [PDF]

iScience
Li J, Wang K, Wang J, Zhong C, Wang S, Peng H, Li Z.   +6 more
europepmc   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source

ARTS Confers Chemoresistance of Breast Cancer by Inducing Apoptosis-Dependent Autophagy via Livin-MDM2-p53 Pathway. [PDF]

Research (Wash D C)
Wang H, Guo Q, Shen Y, Ding K, Chen Y, Wang X, Huang X, Wu Z.   +7 more
europepmc   +1 more source

Reason and Passion: Justice Jackson and the Second Flag Salute Case (Part II)

, 2011
Douglas E. Abrams
openalex   +1 more source