Results 121 to 130 of about 55,682 (249)

Pseudomonas aeruginosa pilin activates the inflammasome [PDF]

, 2011
IL-1 beta is produced from inactive pro-IL-1 beta by activation of caspase-1 brought about by a multi-subunit protein platform called the inflammasome. Many bacteria can trigger inflammasome activity through flagellin activation of the host protein NLRC4.
Agostini, Andersen-Nissen, Arora, Auron, Bergsbaken, Bird, Bitter, Case, Choi, Cornelis, Craig, Dinarello, Evans, Franchi, Franchi, Franchi, Hahn, Hazes, Hsu, Johnson, Kanneganti, Kus, Lightfield, Lindestam Arlehamn, Liu, Marathe, Mariathasan, Mariathasan, Martinon, Martinon, Mattick, Miao, Miao, Miao, Murray, Muruve, Neyt, O'Neill, Perkins, Pier, Proft, Sato, Sato, Sawa, Schroeder, Semmler, Smedley, Sutterwala, Sutterwala, Thornberry, Ting, Vallis, von Götz, Ye, Yu   +54 more
core   +1 more source

High prevalence of a host‐associated Anaplasma lineage in wild coatis (Nasua nasua) from the Brazilian Atlantic Forest

Medical and Veterinary Entomology, EarlyView.
Anaplasma sp. DNA was detected in 47.9% of free‐ranging coatis (Nasua nasua) sampled in Iguaçu National Park, southern Brazil. Molecular analyses revealed a genetically distinct Anaplasma lineage infecting coatis, differing from Anaplasma strains detected in associated tick populations.
Matheus Dias Cordeiro, Paulo César Magalhães‐Matos, Isadora dos Santos Dias, Jônathan David Ribas Chagas, Olívia Zen Gianfrancisco, Ellen Meireles Brandão, Claudia Bezerra da Silva, Bruna de Azevedo Baêta   +7 more
wiley   +1 more source

ERF transcription factor StPti5 is a regulator of endophyte community maintenance in potato

New Phytologist, EarlyView.
Summary We have recently identified an ethylene response factor, StPti5, as a susceptibility factor that negatively regulates immune responses to diverse pathogens. Here, we investigated the role of StPti5 in the processes involved in the colonization of potato with beneficial organisms.
Tjaša Lukan, Karmen Pogačar, Barbara Kraigher, Katja Stare, Teja Grubar Kovačič, Maja Zagorščak, Marko Petek, Polonca Stefanic, Anže Vozelj, Valentina Levak, Tjaša Mahkovec Povalej, Juan M. García, Maria J. Pozo, Eva Álvarez, José M. Franco‐Zorrilla, Maja Križnik, Špela Baebler, Ines Mandić‐Mulec, Kristina Gruden   +18 more
wiley   +1 more source

Flagellin gene sequence evolution in Salmonella

Infection, Genetics and Evolution, 2007
Salmonella exhibits 70 serologically distinct flagellins, used internationally to diagnose and track infections. The terminal sequences of flagellin protein subunits are conserved in a range of bacteria and are here used as evolutionary markers to reveal how new serotypes arise.
Chloe K B, Mortimer, Saheer E, Gharbia, Julie M J, Logan, Tansy M, Peters, Catherine, Arnold   +4 more
openaire   +2 more sources

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, EarlyView.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface

Plant Biotechnology Journal, EarlyView.
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng, Shuqin Zheng, Federica Brandizzi, Yiran Liu, Chunlei Li, Congcong Ai, Yujiao Wang, Jiadong Qi, Xiuguo Zhang   +8 more
wiley   +1 more source

Effects of Elevated CO2 on Bean Pod Mottle Virus Infection in Both Incompatible and Compatible Interactions With Phaseolus vulgaris L

Plant, Cell &Environment, Volume 49, Issue 7, Page 4493-4512, July 2026.
ABSTRACT Plant viruses cause significant crop losses, a situation that could worsen due to anthropogenic activities driving global climate change, one factor of which is the increase in atmospheric CO2 concentration. This study assessed the impact of elevated CO2 concentration (eCO2, 1000 vs. 400 ppm) on two genotypes of common bean (Phaseolus vulgaris
Tiffanie Scandolera, Julie Lintz, Ariane Gratias, Ellea Aboud, Simon Rochoux, Maria V. Préjean, Gilles Chatel Innocenti, Marie Garmier, Gianluca Teano, Juan C. Alvarez‐Diaz, Graham Noctor, Valérie Geffroy, Stéphanie Pflieger   +12 more
wiley   +1 more source

A Non‐Host Pathogen Elicitor Induces Blast Resistance Mediated by OsNAC78‐Pir7b Module in Rice

Plant, Cell &Environment, EarlyView.
ABSTRACT Plants exhibit broad‐spectrum and persistent resistance induced by non‐host pathogens. Previous studies have found that syringolin A secreted by Pseudomonas syringae pv. syringae can activate the expression of defense‐related gene Pir7b in non‐host rice, but the underlying mechanism remains ambiguous.
Yunjie Xie, Yuling Lai, Xingqian Wu, Xiangzhen Yu, Jingwen Wei, Mengge Chen, Yongsheng Zhu, Liping Chen, Hongguang Xie, Qiuhua Cai, Huaan Xie, Jianfu Zhang   +11 more
wiley   +1 more source

Conformational adaptability of the terminal regions of flagellin

Biophysical Journal, 1992
Secondary structure formation in the disordered terminal regions of flagellin were studied by circular dichroic (CD) spectroscopy, Fourier transform infrared spectroscopy, and x-ray diffraction. The terminal regions of flagellin are known to form alpha-helical bundles upon polymerization into flagellar filaments. We found from comparative CD studies of
Vonderviszt, F., Sonoyama, M., Tasumi, M., Namba, K.   +3 more
openaire   +2 more sources

Shigella Effector VirA Suppresses Plant Immunity by Compromising PRA1.F3‐Dependent Accumulation of FLS2 at the Plasma Membrane

Plant, Cell &Environment, EarlyView.
ABSTRACT Surface immune receptors such as flagellin‐sensitive 2 (FLS2) are critical for plant defence, and their accumulation at the plasma membrane is tightly controlled by the endomembrane system. Here, we identify the Arabidopsis thaliana prenylated Rab acceptor PRA1.F3 as a positive regulator required for efficient accumulation of FLS2 at the ...
Sung Hee Jo, Sukyoung Jung, Myoung Hui Lee, Inhwan Hwang, Jeong Mee Park   +4 more
wiley   +1 more source