Results 131 to 140 of about 55,682 (249)

Chemical treatment rescues reduced growth of the autoimmune mutant chs3‐2D without compromising its immune responses

open access: yesPlant Biology, EarlyView.
We generated a compound by chemical modification that can efficiently rescue growth without decreasing the immune response of the chs3‐2D autoimmune mutants, thus chemically uncoupling its growth–defence trade‐off. Abstract Plant development in many species including Arabidopsis relies on the accurate balance between growth and defence.
M. Keijzer   +5 more
wiley   +1 more source

The role of neutrophils in the pathophysiology of inflammatory bowel diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens   +8 more
wiley   +1 more source

Structural engineering of flagellin as vaccine adjuvant: quest for the minimal domain of flagellin for TLR5 activation

open access: yesMolecular Biology Reports
Abstract Flagellin stimulates Toll-like receptor 5 (TLR5), triggering both innate and adaptive immune responses, making it a potential vaccine adjuvant. On mucosal surfaces, flagellin induces a strong release of cytokines, chemokines, and immunoglobulins. When used in its free monomeric form, flagellin has been shown to enhance immune
Afzal, Haroon   +2 more
openaire   +2 more sources

Histiocytes: Multifaceted Regulators of Health and Disease

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Role of Gram‐Negative Bacterial Infections in Acute‐On‐Chronic Liver Failure

open access: yesLiver International, Volume 46, Issue 7, July 2026.
ABSTRACT Acute‐on‐chronic liver failure (ACLF) is a systemic disease characterised by an acute clinical deterioration of pre‐existing liver cirrhosis leading to multiple organ failure due to systemic inflammation. It may be triggered by the translocation of bacteria and bacterial compounds across the gut barrier.
Camilla Cadoli   +5 more
wiley   +1 more source

Polyphosphates Attenuate Interleukin‐12 Production in Macrophages Infected With Legionella pneumophila

open access: yesThe FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Legionella pneumophila infection leads to the release of pathogen‐associated molecular patterns, which recruits the adaptor protein MYD88, initiating both activating (e.g., NF‐κB) and inhibitory (e.g., PI3K/AKT) signaling pathways that regulate IL‐12 gene expression.
Kara Vasilew   +12 more
wiley   +1 more source

Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Wheat (Triticum aestivum L.), a foundation of global food security, faces persistent threats from stripe rust caused by Puccinia striiformis f. sp. tritici (Pst). The pathogen thrives in cool and humid environments and regularly causes epidemics that lead to severe yield losses.
Farkhandah Jan   +11 more
wiley   +1 more source

Polyphasic Characterization of Acetobacter indonesiensis UNPADCC 01‐5 Isolated From a Traditional Fermented Food, Oncom Merah

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
The polyphasic approach (morphology, physiology, biochemistry and genetics) was used to characterize Acetobacter indonesiensis strain UNPADCC 01‐5, which was isolated from oncom merah. The strain's potential as a culture for acidic fermentations and a biofunctional agent was supported by its adaptive characteristics, which included acid tolerance ...
Yolani Syaputri   +9 more
wiley   +1 more source

The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes

open access: yesMolecular Oral Microbiology, Volume 41, Issue 3, Page 131-144, June 2026.
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes   +6 more
wiley   +1 more source

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