Results 61 to 70 of about 55,682 (249)

Halobacterial flagellins are sulfated glycoproteins.

Journal of Biological Chemistry, 1985
The cell-surface glycoprotein of Halobacteria contains oligosaccharides of the type Glc4----1GlcA4----1GlcA4----1GlcA (where GlcA indicates glucuronic acid) with a sulfate group attached to each of the GlcA residues. We report here that in addition to this cell-surface glycoprotein, the halobacterial flagellar proteins (recently described by Alam, M ...
Wieland, F., Pauli, G., Sumper, Manfred
openaire   +3 more sources

Cloning, Expression, and Purification of Pseudomonas aeruginosa Flagellin, and Characterization of the Elicited Anti-Flagellin Antibody [PDF]

Iranian Red Crescent Medical Journal, 2016
Pseudomonas aeruginosa is an important opportunistic human pathogen that causes serious infections in immunocompromised hosts. The single polar flagellum is an important factor in both virulence and colonization.As flagellin is the major component of the flagellar filament, the main aims of the present study are to identify, clone, express, and purify ...
Behrouz, Bahador, Amirmozafari, Nour, Khoramabadi, Nima, Bahroudi, Mahboobeh, Legaee, Parisa, Mahdavi, Mehdi   +5 more
openaire   +2 more sources

Ciclopirox Olamine Inhibits the NLRP3 Inflammasome to Alleviate Inflammatory Diseases

Advanced Science, EarlyView.
There is no drug targeting the NLRP3 inflammasome that has been approved for use in clinical settings. Ciclopirox olamine (CPX), an antifungal agent approved by the US Food and Drug Administration (FDA), is identified as a specific and potent NLRP3 inflammasome inhibitor. CPX targets the NACHT domain of NLRP3 at Y381 to impair NLRP3 oligomerization and
Xinyu Xia, Hui You, Ke Zhang, Hui Jiang, Hongping Liu, Lianghua Liu, Aijie Zhang, You Zhou   +7 more
wiley   +1 more source

Evidence for recombination in the flagellin locus of Campylobacter jejuni: implications for the flagellin gene typing scheme [PDF]

Journal of Clinical Microbiology, 1997
The flagellin subunit of the flagellar filament in Campylobacter jejuni is encoded by two highly homologous tandem genes, flaA and flaB. The flaA gene was sequenced in 18 strains of C. jejuni, including isolates from three outbreak groups. Sequences obtained were compared with flaA sequences available in the GenBank database, and all were analyzed for ...
C S, Harrington, F M, Thomson-Carter, P E, Carter   +2 more
openaire   +2 more sources

Structure and Intermolecular Interactions between L-Type Straight Flagellar Filaments. [PDF]

, 2017
Bacterial mobility is powered by rotation of helical flagellar filaments driven by rotary motors. Flagellin isolated from the Salmonella Typhimurium SJW1660 strain, which differs by a point mutation from the wild-type strain, assembles into straight ...
Dogic, Zvonimir, Dvir, Tom, Ginsburg, Avi, Louzon, Daniel, Raviv, Uri, Schwenger, Walter   +5 more
core  

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Flagellin attenuates experimental sepsis in a macrophage-dependent manner

Critical Care, 2019
Background Sepsis is the leading cause of death among critically ill patients, and no specific therapeutic agent is currently approved for the treatment of sepsis. Methods We assessed the effects of flagellin administration on survival, bacterial burden,
Xiaoliang Yang, Yibing Yin, Xingxing Yan, Zebo Yu, Yi Liu, Ju Cao   +5 more
doaj   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

An immune receptor complex evolved in soybean to perceive a polymorphic bacterial flagellin

Nature Communications, 2020
Ralstonia solanacearum evades plant immunity by producing an atypical flagellin protein, thus causing bacterial wilt disease. Here, Wei et al. show that soybean has evolved a divergent flagellin receptor that recognises R.
Yali Wei, Alexandra Balaceanu, Jose S. Rufian, Cécile Segonzac, Achen Zhao, Rafael J. L. Morcillo, Alberto P. Macho   +6 more
doaj   +1 more source

Modelling bacterial flagellar growth

, 2011
The growth of bacterial flagellar filaments is a self-assembly process where flagellin molecules are transported through the narrow core of the flagellum and are added at the distal end.
Schmitt, Maximilian, Stark, Holger
core   +1 more source