Results 41 to 50 of about 30,529 (162)
Subtilase SBT5.2 inactivates flagellin immunogenicity in the plant apoplast
Nature CommunicationsMost angiosperm plants recognise the 22-residue flagellin (flg22) epitope in bacterial flagellin via homologs of cell surface receptor FLS2 (flagellin sensitive-2) and mount pattern-triggered immune responses.
Pierre Buscaill +9 more
doaj +1 more source
Harnessing flagellin of Ligilactobacillus agilis as a surface display scaffold for an HIV-1 epitope
Applied and Environmental MicrobiologyLactic acid bacteria (LAB) are promising mucosal vaccine vectors due to their safety, immunostimulatory properties, and the availability of genetic tools for certain strains.
Shunya Suzuki +2 more
doaj +1 more source
Mediators of Inflammation, 2010 Background. Bacterial flagellin triggers inflammation in mammalian cells via Toll-like receptor (TLR) 5. Release of the chemokine IL-8 in response to flagellin involves NF-κB, p38 MAP kinase, and phosphatidylinositol 3-kinase (PI3K).
Sabine M. Ivison +7 more
doaj +1 more source
Cloning, Expression, and Purification of Pseudomonas aeruginosa Flagellin, and Characterization of the Elicited Anti-Flagellin Antibody [PDF]
Iranian Red Crescent Medical Journal, 2016 Pseudomonas aeruginosa is an important opportunistic human pathogen that causes serious infections in immunocompromised hosts. The single polar flagellum is an important factor in both virulence and colonization.As flagellin is the major component of the flagellar filament, the main aims of the present study are to identify, clone, express, and purify ...
Behrouz, Bahador +5 more
openaire +2 more sources
Vaccines, 2020 Flagellin from bacteria elicits a proinflammatory immune response and may act as a vaccine adjuvant. In this study, we evaluated the adjuvant effect of the N-terminus of flagellin (residues 1–99) when linked to an antigen (a truncated, conserved domain ...
Thu-Dung Doan +3 more
doaj +1 more source
Evidence for recombination in the flagellin locus of Campylobacter jejuni: implications for the flagellin gene typing scheme [PDF]
Journal of Clinical Microbiology, 1997 The flagellin subunit of the flagellar filament in Campylobacter jejuni is encoded by two highly homologous tandem genes, flaA and flaB. The flaA gene was sequenced in 18 strains of C. jejuni, including isolates from three outbreak groups. Sequences obtained were compared with flaA sequences available in the GenBank database, and all were analyzed for ...
C S, Harrington +2 more
openaire +2 more sources
Pharmaceutics, 2019 The great advantage of virus-like particle (VLP) nano-vaccines is their structural identity to wild-type viruses, ensuring that antigen-specific B-cells encounter viral proteins in their natural conformation.
Cornelia Barnowski +4 more
doaj +1 more source
CD2-1, the C-Terminal Region of Flagellin, Modulates the Induction of Immune Responses in Rice
Molecular Plant-Microbe Interactions, 2015 Flagellin from the rice avirulent N1141 strain of Acidovorax avenae functions as a pathogen-associated molecular pattern (PAMP) and induces PAMP-triggered immunity (PTI) in rice.
Yuya Katsuragi +7 more
doaj +1 more source
Scientific Reports, 2019 Many links between gut microbiota and disease development have been established in recent years, with particular bacterial strains emerging as potential therapeutics rather than causative agents. In this study we describe the immunostimulatory properties
Delphine L. Lauté-Caly +9 more
doaj +1 more source
Aeromonas hydrophila flagella glycosylation: involvement of a lipid carrier.
PLoS ONE, 2014 Polar flagellin proteins from Aeromonas hydrophila strain AH-3 (serotype O34) were found to be O-glycosylated with a heterogeneous glycan. Mutants unable to produce WecP or Gne enzymes showed altered motility, and the study of their polar flagellin ...
Susana Merino +5 more
doaj +1 more source