Results 31 to 40 of about 37,829 (243)

Flagellin Encoded in Gene-Based Vector Vaccines Is a Route-Dependent Immune Adjuvant. [PDF]

PLoS ONE, 2016
Flagellin has been tested as a protein-based vaccine adjuvant, with the majority of studies focused on antibody responses. Here, we evaluated the adjuvant activity of flagellin for both cellular and humoral immune responses in BALB/c mice in the setting ...
Hamada F Rady, Guixiang Dai, Weitao Huang, Judd E Shellito, Alistair J Ramsay   +4 more
doaj   +1 more source

Halobacterial flagellins are encoded by a multigene family. Characterization of five flagellin genes.

Journal of Biological Chemistry, 1988
Purified flagellar filaments of Halobacterium halobium contain three different protein species based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. These proteins were designated as flagellins Fla I, Fla II, and Fla III and were characterized as sulfated glycoproteins with N-glycosidically linked oligosaccharides of the type GlcA-(1----4)
L, Gerl, M, Sumper
openaire   +4 more sources

Classification of Bacillus subtilis flagellins [PDF]

Journal of Bacteriology, 1977
Purified flagellins derived from 16 strains of Bacillus subtilis were classified into at least five distinct groups on the basis of their reaction with antiflagellar filament antibody and antiflagellin antibody. This classification was in good accord with that derived independently on the basis of amino acid analyses of the flagellins.
M I, Simon, S U, Emerson, J H, Shaper, P D, Bernard, A N, Glazer   +4 more
openaire   +2 more sources

Pseudaminic acid on Campylobacter jejuni flagella modulates dendritic cell IL-10 expression via Siglec-10 receptor: a novel flagellin-host interaction. [PDF]

, 2014
INTRODUCTION: Campylobacter jejuni is a leading cause of bacterial gastroenteritis worldwide. At present the identity of host-pathogen interactions that promote successful bacterial colonisation remain ill defined.
Crocker, Paul R., Stephenson, Holly N, Escors, David, Copland, Alastair, Crocker, Paul R, Wren, Brendan W, Dorrell, Nick, Jones, Hannah, Stephenson, Holly N., Wren, Brendan W., Mills, Dominic C, Milioris, Enea, Mills, Dominic C., Bajaj-Elliott, Mona   +13 more
core   +1 more source

Rapid Preparation of Unsheathed Bacterial Flagella

Bio-Protocol, 2015
The flagellum is required for bacterial swimming and swarming motility. In the biphasic Salmonella enterica serovar Typhimurium (S. Typhimurium), the flagellar filament is build up by two distinct monomeric subunits, flagellin FliC and FljB.
Soazig Le Guyon, Mikael Rhen, Ute Römling   +2 more
doaj   +1 more source

NLRC4 Inflammasome-Driven Immunogenicity of a Recombinant MVA Mucosal Vaccine Encoding Flagellin

Frontiers in Immunology, 2018
Bacterial flagellin enhances innate and adaptive immune responses and is considered a promising adjuvant for the development of vaccines against infectious diseases and cancer.
Stephanie L. Sanos, Ronny Kassub, Marco Testori, Marlene Geiger, Juliane Pätzold, Raphael Giessel, Johanna Knallinger, Barbara Bathke, Fabienne Gräbnitz, Kay Brinkmann, Paul Chaplin, Mark Suter, Hubertus Hochrein, Henning Lauterbach   +13 more
doaj   +1 more source

Characterizations of IBV-Flagellin-SAPN and Flagellin-SAPN constructs.

, 2018
(A) Dynamic light scattering of IBV-Flagellin-SAPN. (B) Dynamic light scattering of Flagellin-SAPN. (C) Transmission electron microscopy of IBV-Flagellin-SAPN and (D) Transmission electron microscopy of Flagellin-SAPN.
Antonio Garmendia (5748935), Mazhar I. Khan (4994465), Zeinab H. Helal (5748926), Jianping Li (300447), Christopher P. Karch (5748929), Neha Mishra (4333477), Theodore Girshick (5748932), Peter Burkhard (125115)   +7 more
core   +1 more source

The HP0256 gene product is involved in motility and cell envelope architecture of Helicobacter pylori [PDF]

, 2010
Background Helicobacter pylori is the causative agent for gastritis, and peptic and duodenal ulcers. The bacterium displays 5-6 polar sheathed flagella that are essential for colonisation and persistence in the gastric mucosa.
Caly, Delphine L., O\u27Toole, Paul W., Penn Charles W, Stanley A Moore, Douillard, FP, Douillard, François P., Ryan, KA, Caly Delphine L, Hinds, Jason, Francois P Douillard, Charles W Penn, Moore, SA, Paul W O'Toole, Moore Stanley A, Lane, Michael C., Hinds Jason, Kieran A Ryan, Ryan Kieran A, Lane Michael C, Michael C Lane, Delphine C Caly, O'Toole Paul W, O'Toole, PW, Ryan, Kieran A., Penn, Charles, Caly, DL, Hinds, J, Penn, CW, Penn, Charles W., Jason Hinds, Lane, MC, Moore, Stanley A., Douillard François P, O'Toole, Paul W.   +33 more
core   +1 more source

Flagellin/TLR5 Stimulate Myeloid Progenitors to Enter Lung Tissue and to Locally Differentiate Into Macrophages

Frontiers in Immunology, 2021
Toll-like receptor 5 (TLR5) is the receptor of bacterial Flagellin. Reportedly, TLR5 engagement helps to combat infections, especially at mucosal sites, by evoking responses from epithelial cells and immune cells. Here we report that TLR5 is expressed on
Xin Lei, Xin Lei, Jara Palomero, Iris de Rink, Tom de Wit, Tom de Wit, Martijn van Baalen, Yanling Xiao, Yanling Xiao, Jannie Borst, Jannie Borst   +10 more
doaj   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source