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Essential Role of CFAP53 in Sperm Flagellum Biogenesis
The sperm flagellum is essential for male fertility. Despite vigorous research progress toward understanding the pathogenesis of flagellum-related diseases, much remains unknown about the mechanisms underlying the flagellum biogenesis itself.
Bingbing Wu+33 more
doaj +2 more sources
The optimal elastic flagellum [PDF]
Motile eukaryotic cells propel themselves in viscous fluids by passing waves of bending deformation down their flagella. An infinitely long flagellum achieves a hydrodynamically optimal low-Reynolds number locomotion when the angle between its local tangent and the swimming direction remains constant along its length.
Saverio E. Spagnolie, Eric Lauga
arxiv +6 more sources
Mechanics of a Flagellum [PDF]
CONSIDER a simple homogeneous filament with a wave passing in the direction indicated and suppose that the filament is immersed in water (a). Allow also that the wave is passing along the filament with both an increase in velocity and amplitude and hence an increase in resistance from the water.
A. G. Lowndes
openalex +2 more sources
Assembly and Dynamics of the Bacterial Flagellum.
The bacterial flagellar motor is the most complex structure in the bacterial cell, driving the ion-driven rotation of the helical flagellum. The ordered expression of the regulon and the assembly of the series of interacting protein rings, spanning the ...
J. Armitage, R. Berry
semanticscholar +3 more sources
An orphan kinesin controls trypanosome morphology transitions by targeting FLAM3 to the flagellum.
Trypanosoma brucei undergoes life cycle form transitions from trypomastigotes to epimastigotes in the insect vector by re-positioning the mitochondrial genome and re-locating the flagellum and flagellum-associated cytoskeletal structures.
Tai An, Ziyin Li
doaj +2 more sources
The Flagellum of Trypanosomes [PDF]
Eukaryotic cilia and flagella are cytoskeletal organelles that are remarkably conserved from protists to mammals. Their basic unit is the axoneme, a well-defined cylindrical structure composed of microtubules and up to 250 associated proteins. These complex organelles are assembled by a dynamic process called intraflagellar transport.
Linda Kohl, Philippe Bastin
openalex +7 more sources
A Flagellum-specific Calcium Sensor [PDF]
The flagellar calcium-binding protein (FCaBP) of the flagellated protozoan Trypanosoma cruzi associates with the flagellar membrane via its N-terminal myristate and palmitate moieties in a calcium-modulated, conformation-dependent manner. This mechanism of localization is similar to that described for neuronal calcium sensors, which undergo calcium ...
Kathryn T. Buchanan+7 more
openalex +4 more sources
The Role of the Bacterial Flagellum in Adhesion and Virulence
The bacterial flagellum is a complex apparatus assembled of more than 20 different proteins. The flagellar basal body traverses the cell wall, whereas the curved hook connects the basal body to the whip-like flagellar filament that protrudes several µm ...
J. Haiko, B. Westerlund-Wikström
semanticscholar +5 more sources
Structures of the stator complex that drives rotation of the bacterial flagellum
The bacterial flagellum is the prototypical protein nanomachine and comprises a rotating helical propeller attached to a membrane-embedded motor complex.
J. Deme+10 more
semanticscholar +2 more sources
Ccdc38 is required for sperm flagellum biogenesis and male fertility in mice.
The sperm flagellum is essential for male fertility, and defects in flagellum biogenesis are associated with male infertility. Deficiency of CCDC42 is specifically associated with malformation of mouse sperm flagella.
Ruidan Zhang+12 more
semanticscholar +1 more source