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Essential Role of CFAP53 in Sperm Flagellum Biogenesis
The sperm flagellum is essential for male fertility. Despite vigorous research progress toward understanding the pathogenesis of flagellum-related diseases, much remains unknown about the mechanisms underlying the flagellum biogenesis itself.
Bingbing Wu+33 more
doaj +2 more sources
An orphan kinesin controls trypanosome morphology transitions by targeting FLAM3 to the flagellum.
Trypanosoma brucei undergoes life cycle form transitions from trypomastigotes to epimastigotes in the insect vector by re-positioning the mitochondrial genome and re-locating the flagellum and flagellum-associated cytoskeletal structures.
Tai An, Ziyin Li
doaj +2 more sources
Structures of the stator complex that drives rotation of the bacterial flagellum
The bacterial flagellum is the prototypical protein nanomachine and comprises a rotating helical propeller attached to a membrane-embedded motor complex.
J. Deme+10 more
semanticscholar +2 more sources
Ccdc38 is required for sperm flagellum biogenesis and male fertility in mice.
The sperm flagellum is essential for male fertility, and defects in flagellum biogenesis are associated with male infertility. Deficiency of CCDC42 is specifically associated with malformation of mouse sperm flagella.
Ruidan Zhang+12 more
semanticscholar +1 more source
Basal body positioning is controlled by flagellum formation in Trypanosoma brucei. [PDF]
To perform their multiple functions, cilia and flagella are precisely positioned at the cell surface by mechanisms that remain poorly understood. The protist Trypanosoma brucei possesses a single flagellum that adheres to the cell body where a specific ...
Sabrina Absalon+9 more
doaj +1 more source
Eversion and withdrawal of an intromittent organ before sexual maturation prepares male beetles for copulation [PDF]
Some species of criocerine beetles have a hyper-elongated part of the intromittent organ called a flagellum. In resting position, the flagellum is stored in a specialized internal sac in the intromittent organ. This specialized state of the flagellum and
Yoko Matsumura, Takuya Kubo
doaj +1 more source
Flagellar energy costs across the tree of life
Flagellar-driven motility grants unicellular organisms the ability to gather more food and avoid predators, but the energetic costs of construction and operation of flagella are considerable.
Paul E Schavemaker, Michael Lynch
doaj +1 more source
Dynamic Hybrid Flagellar Motors—Fuel Switch and More
Flagellar motors are intricate rotating nanomachines that are powered by transmembrane ion gradients. The stator complexes are the powerhouses of the flagellar motor: They convert a transmembrane ion gradient, mainly of H+ or Na+, into rotation of the ...
Kai M. Thormann
doaj +1 more source
Axonemal dynein motors are large multi-subunit complexes that drive ciliary movement. Cytoplasmic assembly of these motor complexes involves several co-chaperones, some of which are related to the R2TP co-chaperone complex.
Jennifer Lennon+3 more
doaj +1 more source
The pathogenesis of Crohn's disease (CD) is multifactorial and involves genetic susceptibility, environmental triggers and intestinal microbiota. Adherent-invasive Escherichia coli (AIEC) are flagellated bacteria more prevalent in CD patients than in ...
G. Sevrin+7 more
semanticscholar +1 more source