Results 11 to 20 of about 80,987 (294)

The Flagellum of Trypanosomes [PDF]

, 2005
Eukaryotic cilia and flagella are cytoskeletal organelles that are remarkably conserved from protists to mammals. Their basic unit is the axoneme, a well-defined cylindrical structure composed of microtubules and up to 250 associated proteins. These complex organelles are assembled by a dynamic process called intraflagellar transport.
Kohl, Linda, Bastin, Philippe
openaire   +4 more sources

Polo-like kinase phosphorylation of the orphan kinesin KIN-G negatively regulates centrin arm biogenesis in Trypanosoma brucei [PDF]

eLife
The unicellular parasite Trypanosoma brucei assembles a motile flagellum that is required for locomotion, cell division plane placement, and cell-cell communication.
Yasuhiro Kurasawa, Qing Zhou, Kyu Joon Lee, Huiqing Hu, Ziyin Li   +4 more
doaj   +2 more sources

A chain mechanism for flagellum growth [PDF]

Nature, 2013
Bacteria swim by means of long flagella extending from the cell surface. These are assembled from thousands of protein subunits translocated across the cell membrane by an export machinery at the base of each flagellum. Unfolded subunits then transit through a narrow channel at the core of the growing flagellum to the tip, where they crystallize into ...
Evans, Lewis DB, Poulter, Simon, Terentjev, Eugene M, Hughes, Colin, Fraser, Gillian M   +4 more
openaire   +6 more sources

Disruption of Leishmania flagellum attachment zone architecture causes flagellum loss [PDF]

, 2023
Leishmania are flagellated eukaryotic parasites that cause leishmaniasis and are closely related to the other kinetoplastid parasites such as Trypanosoma brucei. In all these parasites there is a cell membrane invagination at the base of the
Vaughan, Sue, Sunter, Jack D., Halliday, Clare, de Liz, Laryssa Vanessa   +3 more
core   +6 more sources

CEP164C regulates flagellum length in stable flagella [PDF]

, 2020
Cilia and flagella are required for cell motility and sensing the external environment and can vary in both length and stability. Stable flagella maintain their length without shortening and lengthening and are proposed to “lock” at the end of growth ...
Sue Vaughan, Vaughan, Sue, Madison Atkins, Vaughan, Susan, Jack Sunter, Eloïse Bertiaux, Dean, Samuel Dale, Samuel Dale Dean, Philippe Bastin, Shafiq, Shahaan, Týč, Jiří, Jiří Týč, Sunter, Jack, Dean, Samuel, Bertiaux, Eloïse, Bastin, Philippe, Artur Leonel De Castro Neto, Atkins, Madison, Ahmed, Manu, Sunter, Jack D., De Castro Neto, Artur Leonel, Shahaan Shafiq, Manu Ahmed   +22 more
core   +7 more sources

Essential Role of CFAP53 in Sperm Flagellum Biogenesis

Frontiers in Cell and Developmental Biology, 2021
The sperm flagellum is essential for male fertility. Despite vigorous research progress toward understanding the pathogenesis of flagellum-related diseases, much remains unknown about the mechanisms underlying the flagellum biogenesis itself.
Bingbing Wu, Bingbing Wu, Xiaochen Yu, Xiaochen Yu, Xiaochen Yu, Xiaochen Yu, Xiaochen Yu, Chao Liu, Lina Wang, Tao Huang, Tao Huang, Tao Huang, Tao Huang, Tao Huang, Gang Lu, Gang Lu, Gang Lu, Gang Lu, Gang Lu, Gang Lu, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Wei Li, Wei Li, Hongbin Liu, Hongbin Liu, Hongbin Liu, Hongbin Liu, Hongbin Liu, Hongbin Liu   +33 more
doaj   +1 more source

Basal body positioning is controlled by flagellum formation in Trypanosoma brucei. [PDF]

PLoS ONE, 2007
To perform their multiple functions, cilia and flagella are precisely positioned at the cell surface by mechanisms that remain poorly understood. The protist Trypanosoma brucei possesses a single flagellum that adheres to the cell body where a specific ...
Sabrina Absalon, Linda Kohl, Carole Branche, Thierry Blisnick, Géraldine Toutirais, Filippo Rusconi, Jacky Cosson, Mélanie Bonhivers, Derrick Robinson, Philippe Bastin   +9 more
doaj   +1 more source

The trypanosome flagellum [PDF]

Journal of Cell Science, 2003
African Trypanosomes are flagellated protozoan parasites that cause sleeping sickness in humans and Nagana in cattle. During its life cycle, Trypanosoma brucei alternates between an insect vector (tsetse fly) and a mammalian host.
Vaughan, S, Gull, K
openaire   +2 more sources

Eversion and withdrawal of an intromittent organ before sexual maturation prepares male beetles for copulation [PDF]

Royal Society Open Science, 2017
Some species of criocerine beetles have a hyper-elongated part of the intromittent organ called a flagellum. In resting position, the flagellum is stored in a specialized internal sac in the intromittent organ. This specialized state of the flagellum and
Yoko Matsumura, Takuya Kubo
doaj   +1 more source

The KIF6-RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly. [PDF]

Adv Sci (Weinh)
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Xie C, Yi S, Lin X, Zhang S, Wang W, Yuan S, Meng L, Li Y, Tan C, Wei C, Yu Y, Liang Y, Zhang H, Hu L, Lu G, He W, Zhang Q, Du J, Lin G, Tu C, Tan YQ.   +20 more
europepmc   +2 more sources